14 1260 Infinity Binary LC - System User Guide
1 The Agilent 1260 Infinity Binary LC - Product Description
System Components
1260 Infinity High Performance Degasser (G4225A)
The Agilent 1260 Infinity High Performance Degasser , model G4225A, 
comprises four separate vacuum chambers with semipermeable tubings, a 
vacuum pump and control assembly. When the vacuum degasser is 
switched on, the control assembly turns on the vacuum pump, which 
generates a low pressure in the vacuum chambers. The pressure is 
measured by a pressure sensor. The vacuum degasser maintains the low 
pressure by a controlled leak in the air inlet filter and a regulation of the 
vacuum pump using the pressure sensor. 
The LC pump draws the solvents from their bottles through the 
semipermeable tubes of the vacuum chambers. When solvents pass through 
the vacuum chambers any dissolved gas in the solvents permeates through 
the tubings into the vacuum chambers. The solvents will be degassed when 
leaving the outlets of the vacuum degasser.
Figure 3 Overview (only one of the four solvent channels is shown)
Sensor
Solvent
4 separate vacuum chambers
Vacuum container
UHPLC 
Pump
Vacuum 
pump
Control 
circuit