GE Xcellerex XDM Series - User Manual

GE Xcellerex XDM Series

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Xcellerex

™

XDM 50-1000, XDUO

100-1000 mixers

Operating Instructions

Original instructions

Translation disc enclosed

Table of Contents

Questions and Answers

D
David BarnesDec 1, 2025
What to do if temperature control unit (TCU) does not receive setpoint data on GE Mixer?
- K
  kingjohnDec 1, 2025
  If the Temperature Control Unit (TCU) does not receive setpoint data (temperature is not regulated, mixer vessel jacket does not feel warm, TCU does not sound as running): * Ensure the TCU is powered on. * Check the connection between the I/O Cabinet and the PolyScience™ TCU: 1. Hold the clock button on the left side of the TCU until HL is displayed (a few seconds). 2. Press the clock button repeatedly until CC appears on the left display. 3. If the display message is yes, the connection is working properly. 4. If the display message is no, the connection is not functioning. Check the connection cable between the TCU and PLC. * Check the connection between the I/O Cabinet and the Mokon™TCU: 1. Verify that the controller located on the front of the TCU is pow...
S
Sarah WilliamsAug 25, 2025
What to do if load cell is not functioning as expected on GE Mixer?
- K
  Karen HullAug 25, 2025
  If the load cell is not functioning as expected, consider the following: * Ensure the load cell is properly connected. * Contact the metrology department to perform a cornering test to determine if a load cell has failed. * Verify that there are no physical obstructions blocking the load cell's motion. * Disengage the jacking bolt. Note that weight measurements are inaccurate if the mixer was filled while the jacking bolt was engaged. * Contact your GE representative if you suspect the configuration on the load cell transmitter is incorrect or corrupt. * Schedule a calibration of the load cells.
X
xbradyAug 25, 2025
What to do if weight monitoring error occurs on GE Xcellerex XDM Mixer?
- M
  Mario ArnoldAug 26, 2025
  If you encounter a weight monitoring error, such as a weight display outside the operational range or a weight alarm triggered when the mixer weight is within range, consider the following: * Contact the metrology department to perform a cornering test to determine if a load cell has failed. * Check for any physical obstructions that may be hindering the load cell's motion. Ensure the mixer vessel legs are free. * Disengage the jacking bolt. Note that inaccurate weight measurements can occur if the mixer was filled while the jacking bolt was engaged. * Contact your GE representative if you suspect the weight transmitter configuration is incorrect or corrupt.
C
Cory ShafferAug 27, 2025
What to do if agitator does not start on FlexFactory controlled GE Mixer?
- A
  amberjohnsonAug 27, 2025
  If the agitator does not start on a FlexFactory controlled mixer: * Enable the agitator. * Tap RESET on the local control software screen and start the agitator when the system has been restarted after emergency shutdown. Note: The agitator cannot be started while the system is in the state E-STOP. * If the system is in Manual mode, set the system to Auto mode and specify the setpoint. Note: When the system is in Manual mode the setpoint is ignored.
S
stephensmollyAug 27, 2025
Why is variable frequency drive (VFD) not functioning as expected in GE Mixer?
- C
  Catherine SmithAug 27, 2025
  The variable frequency drive (VFD) might not be functioning as expected due to: * The motor being overloaded. Acknowledge the agitator fault and attempt to restart the motor. If the error persists, contact GE for service. * The power cable not being connected. Connect the power cable. * The drive is broken. Contact your GE representative to replace the drive.
G
Gregory GonzalezSep 18, 2025
What to do if a button on local control panel screen is not working on GE Xcellerex XDM?
- J
  Joshua DavisSep 18, 2025
  Contact your GE representative for possible replacement, as the local control panel screen may be broken.
M
michaelleeSep 15, 2025
What to do if agitator assembly does not fit properly in place on GE Mixer?
- J
  joanpowellSep 15, 2025
  Contact your GE representative to schedule agitator alignment check and maintenance, as the agitator is not properly aligned.
J
Joseph ChaseSep 16, 2025
What to do if the home screen does not show up on the local control panel of GE Mixer?
- G
  Gregory GreenSep 16, 2025
  Contact your GE representative for possible replacement, as the I/O Cabinet may be broken.
D
Dr. Karen Mason MDSep 7, 2025
What to do if pH sensor changes are very slow for the application on GE Xcellerex XDM Mixer?
- S
  Samantha LongSep 7, 2025
  If pH sensor changes are very slow and pH control is not rapid enough for the application, do a study to find the best tuning parameters for your system and available reagents, as the tuning parameters or the concentration of the applied acid or base may not be sufficient.
B
Brett ArmstrongSep 4, 2025
What to do if the pump is not turning on GE Xcellerex XDM Mixer?
- R
  Robert ScottSep 4, 2025
  If the pump is not turning: * Verify that the cause of the E-STOP condition is eliminated, and clear the E-STOP. Try to use the pumps again. * Clear the interlock condition.

GE Xcellerex XDM Series Specifications

General

Type	Single-Use Mixer
Material (Single-Use Bags)	Polyethylene
Sterilization	Gamma irradiation (single-use bags)
Power Supply	230 V, 50/60 Hz
Motor Power	Varies by model
Material	Stainless steel
Weight	Varies by model
Dimensions	Varies by model
Certifications	CE
Impeller Type	Bottom-mounted impeller (specific design varies by model)
Applications	Biopharmaceutical and cell culture applications

Summary

Introduction to Xcellerex Mixers

Important User Information for Xcellerex Mixers

Critical safety information, intended use, and prerequisites for operating XDM and XDUO mixers.

Regulatory Information for Xcellerex Mixers

Lists regulations and standards applicable to XDM and XDUO mixers, including manufacturer details.

Safety Instructions for Xcellerex Mixers

Xcellerex Mixer Safety Precautions

General and specific safety warnings, hazards, and protective measures for safe operation.

Emergency Procedures for Xcellerex Mixers

Steps for emergency shutdown and system restart procedures for XDM and XDUO mixers.

System Description for Xcellerex Mixers

Xcellerex Mixer System Overview

General principles and operation of the XDM and XDUO single-use mixing systems.

Xcellerex XDM Mixer System Description

Details on XDM mixer system hardware, including illustrations and components.

Xcellerex XDM Mixer Safety Hardware

Overview of safety systems such as emergency stop, burst discs, and interlocks.

User Interface for Xcellerex Mixers

Xcellerex Mixer User Interface General Description

Overview of the user interface, home screen, and navigation elements.

Xcellerex Mixer Adjustment and Control Screens

Screens for system information, settings adjustment, and control functions.

Xcellerex Mixer Alarm Screens

Information on alarm overview, status, and configuration screens.

Installation of Xcellerex Mixers

Xcellerex Mixer Installation Safety Precautions

Essential safety measures and warnings specific to the installation process.

Xcellerex Mixer Installation Site Requirements

Requirements for space, electrical power, and environmental conditions for installation.

Xcellerex Mixer Installation Procedure

Steps for moving, electrical installation, and local control software configuration.

Preparation for Xcellerex Mixer Operation

Xcellerex Mixer Preparation Safety Precautions

Safety measures to be taken before preparing the mixer for operation.

Prepare the Disposable Bag for Xcellerex Mixer

Instructions for unpacking and installing the disposable bag assembly.

Prepare and Install Probes for Xcellerex Mixer

Procedures for calibrating and installing pH and conductivity measurement probes.

Operation of Xcellerex Mixers

Xcellerex Mixer Operation Safety Precautions

Safety warnings and precautions related to operating the mixer.

Operating the Xcellerex XDM Mixer

Instructions for starting up and operating the XDM mixer system.

Operating the Xcellerex XDUO Mixer

Instructions for starting up and operating the XDUO mixer using local control software.

Finishing a Batch Run on Xcellerex Mixers

Steps to complete a batch run, including product collection and system shutdown.

Maintenance of Xcellerex Mixers

Xcellerex Mixer Maintenance Safety Precautions

Safety measures required before performing maintenance on the mixer.

Xcellerex Mixer Lock-Out; Tag-Out (LOTO) Procedures

Procedures for safely turning off and on the instrument for maintenance.

Xcellerex Mixer Hardware Maintenance

Information on inspecting jacking bolts and replacing burst discs.

Troubleshooting Xcellerex Mixers

Xcellerex Mixer Agitation Troubleshooting

Troubleshooting common issues related to mixer agitation for XDM and XDUO models.

Xcellerex Mixer pH Control Troubleshooting

Troubleshooting common issues related to pH control for XDUO mixers.

Xcellerex Mixer Pump Troubleshooting

Troubleshooting common issues related to the mixer pumps.

Reference Information for Xcellerex Mixers

Xcellerex Mixer System Specifications

Technical specifications including dimensions, weight, and construction materials.

Xcellerex Mixer Temperature Probe Calibration

Detailed procedures for calibrating the temperature probes.

Appendix A: Information about Appendices

Appendix B: Add and Remove Users

Procedures for managing user accounts in the local control software.

Appendix C: Download Audit and Data Logs

Instructions for downloading audit and data logs to an external computer.

Appendix D: Privacy and Security

Information on cyber security requirements and network connection best practices.

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