Appendix
CoaDATA 501 – Operators Manual 2.1 Page 50
5.5 Mathematics
Computation of Factor for
PT calibration curve:
Determine the 100 % value in s (e.g.12.2 sec) and the 25 % value in sec
(e.g.29.3 sec) from regular plasma in double determination and proceed as
follows:
Computation of Factor:
(25 % Value in sec) – (100 % Value in sec)
(1/25) – (1/100 %) = factor
Example:
( 29.3 – 12.2 )
17.1
(1/25) – (1/100 %)
= 0.04-0.01 = factor = 570
Please only enter the first two digits into the menu, as for example 57!
Computation of PT %
1
(( meas. time-100 %
=
PT %
Range for conversions:
Method Unit from to exceeded
PT: % 2,0 250 error
Ratio 0,1 10 Error
INR 0,1 10 error
Fibrinogen:
g/l 0,4 9,999 error
mg/dl 40 999,9 error
Another limit is the lag phase of the method.
Computation of mean
If in a dual determination the individual results deviate to a larger extent
than permitted by the coefficient of variation, the error message mean error
will be displayed and printed-out.
Extrapolation
PT >100 % linear extrapolation over the last two higher points.
PT <10 % linear extrapolation over the last two lower points.
Fibrinogen: linear extrapolation respectively over the last two points.