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Waters HPLC - Page 112

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3-28 Troubleshooting, Testing, and Maintenance
Reproducibility errors Syringe contains an air
bubble (usually seen at
the top of the syringe)
Remove bubble.
Leaks at the fluid
tubing connections
Check for leakage at the
connections with the
corner of a tissue, and
tighten connection
slightly if the tissue is
moistened.
Seal pack failure Replace seal pack.
Compression check
failed
Syringe contains air
bubble (usually seen at
the top of the syringe)
Remove bubble.
Mobile phase not
properly degassed
Sparge mobile phase.
Leaks at the fluid
tubing connections
Check for leakage at the
connections with the
corner of a tissue, and
tighten connection
slightly if the tissue is
moistened.
High pressure limit on
PUMP SETUP screen
must be at least two
times compression
pressure
Change pressure limit
on the PUMP SETUP
page; change pump flow
to adjust pressure.
Parameters used for
Compression Check
unacceptable for solvent
Repeat the test using
default parameters on
Purge and
COMPressION test
screen. If the test fails
again, perform an
autocalibration and
repeat the test.
Seal pack failure Replace seal pack.
Autoinjector troubleshooting (Continued)
Symptom Possible cause Corrective action

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