Advanced Instruments OsmoPRO Multi-Sample - Interpreting Results

OsmoPRO® Multi-Sample Micro-Osmometer User’s Guide
9
Interpreting Results
Data generated using Advanced Instruments standards and reference solutions may be
analyzed according to the accuracy and precision specifications of the instrument (see
Performance characteristics
).
Laboratories may choose to employ one, two, or three standard deviations (SD) for accuracy
based on what is relevant in their laboratories. For normally distributed data, approximately 68
%
of the individual data values will fall within one standard deviation of the mean, approximately 95%
within two standard deviations, and approximately 99.7% within three standard deviations.
Advanced Instruments
Standards and Reference
Solutions
Precision
Accuracy (mOsm/kg H
2
O)
1 SD 2 SD 3 SD
Clinitrol™ 290 Reference Solution Standard deviation ≤3 mOsm/kg H
2
O 287-293 284-296 281-299
50 mOsm/kg Calibration Standard
Standard deviation ≤3 mOsm/kg H
2
O
47-53
44-56
41-59
100 mOsm/kg Calibration Standard
Standard deviation ≤3 mOsm/kg H
2
O
97-103
94-106
91-109
200 mOsm/kg Calibration Standard
Standard deviation ≤3 mOsm/kg H
2
O
197-203
194-206
191-209
400 mOsm/kg Calibration Standard
Standard deviation ≤3 mOsm/kg H
2
O
397-403
394-406
391-409
500 mOsm/kg Calibration Standard Coefficient of variation ≤0.75% 496-504 492-508 488-512
850 mOsm/kg Calibration Standard Coefficient of variation ≤0.75% 843 -857 836-864 829-871
900 mOsm/kg Calibration Standard Coefficient of variation ≤0.75% 893-907 886-914 879-921
1000 mOsm/kg Calibration Standard Coefficient of variation ≤0.75% 992-1008 984-1016 976-1024
1500 mOsm/kg Calibration Standard
Coefficient of variation ≤0.75%
1488-1512
1476-1524
1464-1536
2000 mOsm/kg Calibration Standard
Coefficient of variation ≤0.75%
1985-2015
1970-2030
1955-2045
Advanced Instruments
Controls
Expected Levels Expected Ranges
Protinol™ Protein-Based
Controls
240 mOsm/kg H
2
O
280 mOsm/kg H
2
O
320 mOsm/kg H
2
O
233-247 mOsm/kg H
2
O
273-287 mOsm/kg H
2
O
313-327 mOsm/kg H
2
O
Renol™ Urine Osmolality Controls
300 mOsm/kg H
2
O
800 mOsm/kg H
2
O
290-310 mOsm/kg H
2
O
790-810 mOsm/kg H
2
O
Protinol and Renol specifications are presented as a range. This range was established based
of stability data and approximates a three standard deviation range of results.