Agilent 708-DS Dissolution Apparatus
Training Manual
Revision A September 2010
P/N: xx-xxxx
For automated sample collection, the Auto Sampling option is available which
is comprised of a sampling manifold with sampling and return cannulas. The
manifold may also include the AutoTemp option which includes individual
temperature probes for each dissolution vessel.
For a hands-free test start, the newly designed Dosage Delivery Module (DDM)
allows for simultaneous or sequential introduction of dosage forms. Lastly, a
Printer may be included to document all critical apparatus settings and events.
2. Instrument Setup
2.1. Physical Setup
Once the 708-DS dissolution apparatus has been delivered to the laboratory
where setup and installation will occur, the steps to begin unpacking and any
applicable qualification begin. The following sections will proceed naturally
through various procedures to ensure a smooth and methodical setup.
2.1.1. Unpacking Equipment / Accessories
Upon delivery of the equipment, some portions of the apparatus will
require some simple assembly. It is important to first inspect all pieces to
ensure no damage has occurred during shipment. The following table
includes many, if not all, of the accessories shipped with the unit:
708-DS Dissolution Apparatus Heater / Circulator
Power Cords 6-pin Cable for Heater / Circulator
Bath Temperature Probe External Vessel Temperature (EVT) Probe
Dissolution Vessels Evaporation Covers
TruAlign™ Blank Vessel Position Covers Evaporation Cover Plugs
DDM Assemblies Basket Shaft Assemblies
Cover Aligners Paddle Shaft Assemblies
DDM Alignment Shafts Vessel Centering Tool
Shaft Locking Collars Thermal Printer Paper
17-mm Open End Wrench 90° Allen Key (for Level Adjustment)
7/64” T-Handle Allen Wrench Stainless Steel Tubing Clamps
Length of Plastic Tubing (1/2” OD) 25-mm Spheres
Clip-on Basket Height Gauge Bubble Level
Technical Documentation CD Rinse Cups
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