The chronaxy corresponds to the time value when ๐ = 0
i.e. ๐ ๏ ๎ต + ๐๐ก if ๐ = 0 therefore ๎ต+๐๐ก = 0 therefore ๐๐ก = ๎ต and ๐ก ๏ ๎ต/๐
Fig. 4
12.1.2 Summary
Electrical stimulation, i.e. reducing resting potential to the stimulation threshold using an electric current, is
a phenomenon that ful๏ฌls a fundamental physiological law.
This shows us that:
1 The factor determining stimulation is the quantity of electrical
charges created by the current.
Stimulation must be considered in terms of the amount of current, which is the
product (๐ผ๐ฅ๐ก) of the intensity (๐ผ) times the duration of the pulse (๐ก).
2 This amount of current ful๏ฌls a fundamental formula:
๐ ๏ ๎ต + ๐๐ก
where ๐ is a linear function of time.
Lapicque expresses this formula in another way by the โintensity - pulse durationโ
ratio: ๐ผ๏๎ต/๐ก+๐and he deduced that
a) the rheobase (๐
โ): minimum intensity that must be reached in order to produce
stimulation using an in๏ฌnite pulse duration
๐
โ = ๐
b) the chronaxy (๐ก๐โ): minimum time in which a current with double the intensity of
that of the rheobase must be applied in order to produce stimulation
๐ก๐โ = ๎ต/๐
We can note that the chronaxy can be calculated mathematically from Weissโ fundamental formula as
shown in Figure 4.