Waters HPLC - Page 98

3-14 Troubleshooting, Testing, and Maintenance
Peak resolution troubleshooting
Are peaks
eluting at correct
retention time?
Resolution
problem
Troubleshoot
retention time
problem
Are peaks
broadening?
(column)
Are peaks
broadening?
(not column)
Check column by
determining plate
count. low?
Replace column
and check plate
count. low?
Inline filter or
guard column
clogged?
Clean/replace filter
or guard column
Continued on next page
Injector/column
tubing diameter
too large?
Use correct
diameter tubing
Detector/column
tubing diameter
too large?
Use correct
diameter tubing
Problem with
injector?
Troubleshoot
injector
Call Waters
technical service
No
Yes
Yes
No
Yes
Yes
No
Yes
Yes
No
No
No
No
Yes
Yes
Yes
No