38 Biotage
®
ELSD-A120 User Manual
4 Using the Detector
General Considerations
Transferring ELSD Temperature Methods
The direct transfer of ELSD operating conditions from other
manufacturers’ ELS detectors to ELSD-A120 will not provide
equivalent performance.
As stated in “Basic Principles of Operation” on page 7, the operating
temperatures of ELSD-A120 are set according to the type of analyte and
not the mobile phase composition as with other ELS detectors. For
example, when HPLC grade water is used as the mobile phase,
ELSD-A120 requires an evaporation temperature between 35 and 40 °C.
Therefore the transfer of operating conditions from other ELSD to
ELSD-A120 is not valid and the only way to ensure that the detector
will provide the optimum analyte signal-to-noise is to follow the
guidelines outlined in “Operational Parameters” on page 9.
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