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IDEXX VetTest* Chemistry Analyzer Operator’s Manual
Urine Protein/UPRO
Urinary protein is determined and compared to the concentration of creatinine in order
to assess the level of renal protein (glomeruli and tubular) loss to determine the urine
protein/creatinine ratio (UPC).
Principal Reason for Performing the Test
To be performed with urine creatinine in order to determine the urine protein to
creatinine ratio (UPC).
Most common abnormality indicated by the test:
Proteinuria indicating early renal failure, protein losing nephropathy.
Sample type and precautions:
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urinary sediment should be demonstrated and urinary tract infection (UTI) via culture
and sensitivity should be ruled out before performing as UTI may mildly to moderately
raise the UPC.
Complementary tests:
Complete urinalysis with culture and sensitivity. Serum chemistries such as creatinine,
BUN, albumin, and globulin.
CBC
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Storage Information:
Handle and store urine samples in closed containers to avoid evaporation and
contamination. Samples may be stored at room temperature for up to four hours.
Refrigerated samples may be stored up to three days. Do not freeze samples.
Do not use hemolyzed specimens as hemoglobin increases results significantly. Intact
red blood cells can be removed via centrifugation.
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