u Manual updates—Download the System Suite installer from the NextSeq 500 support page on the
Illumina website.
Automatic Software Update
1 Select Manage Instrument.
2 Select Software Update.
3 Select Install the update already downloaded from BaseSpace.
4 Select Update to begin the update. A dialog box opens to confirm the command.
5 Follow the prompts in the installation wizard:
a Accept the licensing agreement.
b Review the release notes.
c Review the list of software included in the update.
When the update is complete, the control software restarts automatically.
NOTE
If a firmware update is included, an automatic restart of the system is required after the firmware is updated.
Manual Software Update
1 Download the System Suite installer from the Illumina website and save it to a network location.
Alternatively, copy the software installation file to a portable USB drive.
2 Select Manage Instrument.
3 Select Software Update.
4 Select Manually install the update from the following location.
5 Select Browse to navigate to the location of the software installation file, and then select Update.
6 Follow the prompts in the installation wizard:
a Accept the licensing agreement.
b Review the release notes.
c Review the list of software included in the update.
When the update is complete, the control software restarts automatically.
NOTE
If a firmware update is included, an automatic restart of the system is required after the firmware is updated.
Shut Down the Instrument
1 Select Manage Instrument.
2 Select System Power Options.
3 Select Shut Down.
The Shut Down command safely shuts down the software and turns off instrument power. Wait at least
60 seconds before turning on the instrument again.
Document # 15046563 v04
For Research Use Only. Not for use in diagnostic procedures.
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NextSeq 500 System Guide