Value-added Quality Control
In addition to precise and accurate transfer of fluids, the Echo Liquid Handler has an auditing function that can provide quality
control of fluid samples. The Echo Liquid Handler applies a low-energy sound pulse to the fluid sample in each well, and the
reflected signal is used to calculate the following:
l Aqueous solutions: approximate fluid volume in the well based on the measured fluid height.
l Glycerol-based solutions: fill height and percentage of glycerol concentration (up to 50%).
l Glycerol and salt-based solutions: fill height and impedance measurement in megaRayls (unit of acoustic impedance) up to
2.23 MRayl.
The data can then be uploaded to a LIMS (Laboratory Information Management System) for post transfer processing and analysis.
For example, the following figure shows part of the plate survey of samples in the buffer. The plate survey was saved to CSV
(comma separated values) file format and opened in Microsoft® Excel®.
Figure 4: Example of Aqueous Fluid Thickness Data Imported Into a Spreadsheet for Analysis
19 PN | 001-11665
USER GUIDE | Echo® 525 Liquid Handler User Guide What are the Echo Liquid Handler features?
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