Instruction Manual, November 2016 Page 2
1. Introduction
1.1. CAMAG ADC2
The Automatic Development Chamber (ADC2) permits reproduci-
ble chromatogram development without the need for constant
monitoring by the user. The ADC2 is shipped with a RS232 cable
and built-in interface for connecting to a computer with vision-
CATS/winCATS from which the instrument can be run but it can
be used in Stand-Alone mode too.
By means of ADC2, developing of HPTLC chromatograms will be
reproducible. The user is free from any process monitoring.
The user decides whether and how to precondition the plate, pre-
selects the distance to be migrated by the solvent system and the
drying parameters.
Development proceeds automatically and under controlled condi-
tions. A CCD-sensor monitors the progress of the solvent front;
the distance covered and the time elapsed are continuously dis-
played. On completion of development, the HPTLC plate is dried
with air and finally stays safely protected in the chamber until re-
moved by the user.
If used in Stand-Alone mode all method parameters are entered
via the keypad. Ten complete development programs can be
saved in nonvolatile memory and started at will without PC-
control.
HPTLC plates with a thickness of up to 2.5mm can be used in the
ADC2. If using aluminum foils it is mandatory to utilize a special
foil holder # 115.8363.
The ADC2 controlled by the software permits full control of the
development process by monitoring and reporting all parameters
including all TLC steps of an analysis, i.e. definition of plate mate-
rial, sample application, derivatization, development and evalua-
tion. All data are handled in a cGMP/cGLP compliant environment.
With the appropriate software option, the ADC2 can be used in a
21 CFR Part 11 compliant environment.
1.2. Precautions
• Please read this operating manual before starting the installa-
tion! This manual contains information and warnings the user
has to follow to ensure reliable operation of the instrument
• If the instrument is used in a manner not specified in this man-
ual, the protection provided by the equipment may be impaired
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