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AKTAprocess
GE AKTAprocess User Manual
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Using
the
CIP/AxiChr
om
manifold
option
This
flow
scheme
shows
an
example
of
how
to
use
the
CIP/AxiChrom
manifold
option
for
CIP
on
a
system
configur
ed
with
the
B-pump
option.
F
C
P
XV
-001
A1
A3
A5
A7
A9
A10
A8
A6
A4
A2
B1
B3
B5
B6
B4
B2
P-201 A
P-201 B
FT
-142
PT
-
111
CE/TE-101
XV
-011, 013, 015
XV
-002
XV
-012, 014, 016
XV
-003, 005, 007, 009
XV
-004, 006,
008, 010
XV
-083
XV
-084
XV
-081
XV
-082
CIP3
CIP1
CIP2
CIP4
CIP C
1 2 3
3
P
PT
-115
P
PT
-116
PCV-341
PCV-342
ÄKT
Aprocess
Operating
Instructions
29-0252-49
AA
139
6
Maintenance
6.2
Cleaning
6.2.2
Cleaning-in-place
(CIP)
138
140
Table of Contents
Default Chapter
3
Table of Contents
3
Illustration
3
Decontamination
4
Shutdown
4
1 Introduction
5
About this Manual
6
Important User Information
7
Intended Use
7
Regulatory Information
10
CE Conformity
10
Associated Documentation
14
Nents
14
2 Safety Instructions
16
2.3 Emergency Procedures
16
Safety Precautions
17
General Precautions
17
Personal Protection
19
Installing and Moving
20
Power Supply
23
Labels
30
Emergency Procedures
34
Air Trap Valves
36
Recycling Information
38
Disposal, General Instructions
38
Disposal of Electrical Components
38
Declaration of Hazardous Substances (Dohs)
39
3 System Description
42
Configurations
43
Illustrations of Äktaprocess
44
Standard Components
53
Structural Components
54
Electric Cabinet
54
Control System Components
55
Inlets and Outlets
57
Meters and Sensors
58
System Pump
59
Air Trap
60
Valves
61
Filter Valves
62
Optional Components
65
CIP / Axichrom Manifold
71
Flowchart
72
UNICORN Control System
77
4 Installation
81
Site Requirements
82
Electrical Power
82
Transport
84
Unpack Äktaprocess
86
Äktaprocess Setup
88
Assembly of Äktaprocess
89
Setup of Control System and Network
94
Connect Compressed Air Supply
98
Guidelines for Connections
99
Connect Sample Pump
100
Connect a Column
102
Power Supply
105
5 Operation
110
Prepare the System
112
Start the System and Software
113
Prepare System Components
115
Priming and Leakage Test
118
Set Pressure Control Valve Parameters
121
Final Checks
123
Perform a Run
124
Shut down the System and Software
127
6 Maintenance
128
User Maintenance Schedule
130
Flow Meter
132
Cleaning
134
Important Considerations for Cleaning
136
Cleaning-In-Place (CIP)
138
CIP Hookup
138
General Procedure for CIP and Sanitization
141
Cleaning, General
141
Storage
144
Disassembly and Assembly
146
Calibration of Ph Probe
148
Repair and Calibration
151
Pump Calibration
152
Air Trap Calibration
153
Component Replacement
156
7 Troubleshooting
157
8 Reference Information
163
Specifications
164
Ambient Environment
164
Compressed Air
164
Cabinet
165
Chemical Resistance
167
Gradient Performance
169
Decontamination Report
171
UNICORN Method for System Cip/Sanitization/Rinsing
172
0.00 Filter Inline
172
Further Information
175
Index
176
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Site Preparation Guide
16 pages
5
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GE AKTAprocess Specifications
General
Brand
GE
Model
AKTAprocess
Category
Laboratory Equipment
Language
English
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