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1155.1.2 Prepare system components ........................................................................................................

1185.1.3 Priming and leakage test ................................................................................................................

1215.1.4 Set pressure control valve parameters .....................................................................................

1235.1.5 Final checks ..........................................................................................................................................

1245.2 Perform a run .........................................................................................................................................

1275.3 Shut down the system and software ..........................................................................................

1286 Maintenance .........................................................................................................

1306.1 User maintenance schedule ...........................................................................................................

1346.2 Cleaning ....................................................................................................................................................

1366.2.1 Important considerations for cleaning .....................................................................................

1386.2.2 Cleaning-in-place (CIP) .....................................................................................................................

1416.2.3 General procedure for CIP and sanitization ...........................................................................

1446.3 Storage ......................................................................................................................................................

1466.4 Disassembly and assembly .............................................................................................................

1486.5 Calibration of pH probe .....................................................................................................................

1516.6 Repair and calibration ........................................................................................................................

1526.6.1 Pump calibration ................................................................................................................................

1536.6.2 Air trap calibration .............................................................................................................................

1566.6.3 Component replacement ................................................................................................................

1577 Troubleshooting ...................................................................................................

1638 Reference information ........................................................................................

1648.1 Specifications .........................................................................................................................................

1678.2 Chemical resistance ............................................................................................................................

1698.3 Gradient performance .......................................................................................................................

1718.4 Decontamination report ....................................................................................................................

1728.5 UNICORN method for system CIP/Sanitization/Rinsing ......................................................

1758.6 Further information .............................................................................................................................

176Index .......................................................................................................................

4 ÄKTAprocess Operating Instructions 29-0252-49 AA

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