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Waters 515 HPLC - Replacing the Outlet Check Valve

Waters 515 HPLC
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Cleaning and replacing check valves 4-21
12. Reconnect the inlet and outlet tubing to the pump head. While
tightening the compression screw, hold the housing to prevent it from
turning.
13. Reconnect the eluent supply line to the inlet manifold on the pump.
14. Remove the fitting plug from the pump outlet, then reposition the eluent
reservoir.
15. Prime the pump as described in “Priming the pump” on page 3-15.
Check for leaks.
Replacing the outlet check valve
Required materials
5/16-inch open-end wrench (Startup Kit)
Priming syringe (Startup Kit)
1/2-inch open-end wrench
Fitting plug (Startup Kit)
•Replacement check valve
Methanol
Removing the outlet check valve
To remove the outlet check valve:
1. Purge the pump with methanol as described in “Purging the system” on
page 3-17. If methanol is not miscible with your current eluent, use an
intermediate eluent.
2. Disconnect the eluent supply line from the inlet manifold on the pump.
3. Disconnect the outlet tubing from the pump and install a fitting plug
into the outlet. Tighten the plug with the 5/16-inch wrench.
4. Insert the priming syringe into the luer fitting at the center of the
draw-off valve handle, then turn the handle counterclockwise about
1/2-turn to open the valve.
Caution: Before you continue with this procedure, lower the
eluent reservoir to eliminate gravity flow.

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