Waters ACQUITY UPLC I-Class IVD - Column Manager Maintenance Procedures: (Continued)

Maintenance schedule
July 7, 2014, 715003736IVD Rev. C 41
Replace the column
in-line filter frit
Replace as part of the annual scheduled routine
maintenance and, thereafter, as needed. The
typical failure modes are as follows:
•High back pressure. The column in-line filter
causes a high pressure shutdown. In this case,
disconnect the column. If the system exhibits
pressure decay, check the system pressure at
known conditions. Replace the frit.
•Leak. The system exhibits low back pressure or
shorter retention times.
Replace the column
in-line filter unit
As needed. The typical failure modes are as follows:
•High back pressure. The column in-line causes a
high pressure shutdown. In this case, disconnect
the in-line filter. If the system exhibits pressure
decay, check the system pressure at known
conditions. Replace the frit or entire in-line filter
assembly.
•Leak. This can be detected visibly, using the leak
sensor or by noticing the peak retention times
vary.
•Split peaks. Replace the filter frit.
Clean the device’s
exterior with a soft,
lint-free cloth, or paper
dampened with water
Perform as part of your annual routine scheduled
maintenance and when solvent or dust
accumulates.
Column Manager maintenance procedures: (Continued)
Maintenance
procedure
Frequency