Waters ACQUITY UPLC M-Class - Μsm-FL Recommendations; Properties of Common Solvents

D.3.2 µSM-FL recommendations
• Typical organic sample diluents such as dimethylsulfoxide (DMSO) and dimethylformamide
(DMF) are supported.
• Do not use buffers as needle wash solvents. You can use acids and bases.
D.4
Properties of common solvents
The following table lists the properties for some common chromatographic solvents.
Table D–1: Properties of common solvents
Solvent Vapor pressure mm
Hg (Torr)
Boiling point (°C) Flash point (°C)
Acetonitrile 88.8 at 25 °C 81.6 6
n-butyl acetate 7.8 at 20 °C 126.11 22
n-butyl alcohol 4.4 at 20 °C 117.5 37
n-butyl chloride 80.1 at 20 °C 78.44 -9
Chlorobenzene 8.8 at 20 °C 131.69 28
Chloroform 158.4 at 20 °C 61.15 none
Cyclohexane 77.5 at 20 °C 80.72 -20
Cyclopentane 400 at 20 °C 49.26 -7
o-Dichlorobenzene 1.2 at 20 °C 180.48 66
Dichloromethane 350 at 20 °C 39.75 none
Dimethyl acetamide 1.3 at 25 °C 166.1 70
N,N-
Dimethylformamide
2.7 at 20 °C 153.0 58
Dimethyl sulfoxide 0.6 at 25 °C 189.0 88
1,4-Dioxane 29 at 20 °C 101.32 12
Ethyl alcohol 43.9 at 20 °C 78.32 15
Ethyl ether 442 at 20 °C 34.55 -45
Ethylene dichloride 83.35 at 20 °C 83.48 13
Heptane 35.5 at 20 °C 98.43 -4
Iso-octane 41 at 20 °C 99.24 -12
Isobutyl alcohol 8.8 at 20 °C 107.7 28
Isopropyl alcohol 32.4 at 20 °C 82.26 12
Isopropyl myristate <1 at 20 °C 192.6 164
November 26, 2019, 715003588 Revision C
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