1-10 Waters TQ Detector Overview
MS operating modes
The following table shows the MS operating modes.
The MS1 mode, in which MS1 is used as the mass filter, is the most common
and most sensitive method of performing MS analysis. It is directly analogous
to using a single-quadrupole mass spectrometer.
The MS2 mode of operation is used, with collision gas present, when switching
rapidly between MS and MS/MS operation (for example, in survey scan mode).
It also provides a useful tool for instrument tuning and calibration before
MS/MS analysis and for fault diagnosis.
The selected ion recording (SIR) mode of operation is used as a quantitation
mode when no suitable fragment ion can be found to perform a more specific
multiple reaction monitoring (MRM) analysis.
MS operating modes :
Operating mode MS1 Collision cell MS2
MS1 Resolving
(scanning)
Pass all masses
MS2 Pass all masses Resolving
(scanning)
SIR Resolving (static) Pass all masses
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