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RTCA SP Instrument Operator’s Manual
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Cells are introduced into the wells of the E-Plate 96, making contact with, and attaching
to the sensor-electrode surfaces. e electronic properties of the sensor surfaces are moni-
tored through the RTCA SP Station, which can be placed inside a tissue culture incubator,
and the RTCA Analyzer. is is done under the control of the RTCA So ware on the
RTCA Control Unit, to provide real-time, quantitative information about the biological
status of the cells, including cell number, viability, morphology and cytoskeletal dynamics.
e RTCA Instrument is applicable for a wide variety of cell-based assay applications,
including:
Cell adhesion and spreading
Cell proliferation and di erentiation
Compound-mediated cytotoxicity/Apoptosis
Cell-mediated cytotoxicity
Receptor-mediated signaling
Quality control of cells
Virus-mediated cytopathogenicity
e System is highly quantitative, with excellent accuracy, precision, and ease of use.
e RTCA So ware can be used for simpli ed experimental design and set-up; it will
then direct the instrument to perform the experiment and provide fully automated data
acquisition, data analysis, and data presentation.
Introduction
RTCA SP Instrument
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