Agilent Technologies 5975

Agilent Technologies
Agilent 5975
Series MSD
Operation Manual
for MassHunter

Agilent Technologies 5975 Specifications

General

Ion Source	Electron Ionization (EI)
Analyzer Type	Quadrupole
Dynamic Range	10^6
Category	Mass Spectrometer
Type	Mass Spectrometer
Sensitivity	1 pg OFN S/N ≥ 100:1
Resolution	Unit mass resolution
Ionization Modes	EI (Electron Ionization)
Vacuum System	Turbomolecular pump
Dimensions (W x D x H)	22 x 60 x 48 cm
Weight	34 kg
Power Requirements	100-240 VAC, 50/60 Hz, 600 W

Summary

About This Manual

1 Introduction

General information about the 5975 Series MSD, including hardware, safety warnings, and hydrogen safety.

2 Installing GC Columns

How to prepare, install, and connect GC columns to the MSD.

3 Operating in Electron Impact (EI) Mode

Basic tasks for operating the MSD in EI mode, such as settings, tuning, and pumpdown.

4 Operating in Chemical Ionization (CI) Mode

Additional tasks for operating the MSD in CI mode.

5 General Maintenance

Maintenance procedures common to both EI and CI instruments.

6 CI Maintenance

Maintenance procedures unique to CI MSDs.

1 Introduction

Important Safety Warnings

Crucial safety notices to be aware of when using the MSD.

Hydrogen Safety

Specific safety precautions and hazards related to using hydrogen as a carrier gas.

The 5975 Series MSD

CI MSD Hardware Description

The 5975 Series MSD

Local control panel

CI MSD Hardware Description

Important Safety Warnings

Many internal parts of the MSD carry dangerous voltages

Warns about dangerous voltages within the MSD even when off.

Many parts are dangerously hot

Alerts users to hot components in the MSD that can cause burns.

Electrostatic discharge is a threat to MSD electronics

Explains the risk of ESD to MSD electronics and necessary precautions.

The oil pan under the foreline pump can be a fire hazard

Warns about the fire hazard posed by the foreline pump's oil pan.

Hydrogen Safety

GC precautions

Specific precautions for using hydrogen as a GC carrier gas.

Hydrogen Safety

Dangers unique to GCMSD operation

Dangers specific to GC/MSD operation involving hydrogen.

Precautions

General and equipment-specific precautions for handling hydrogen.

Operating precautions

Specific operating precautions when using hydrogen as a carrier gas.

Hydrogen accumulation in an MSD

Explains how hydrogen can accumulate in the MSD and the risks.

2 Installing GC Columns

To Prepare a Capillary Column for Installation

Details on preparing a capillary column before installation.

To Install a Capillary Column in a SplitSplitless Inlet

Procedure for installing a capillary column into a split/splitless inlet.

To Condition a Capillary Column

Steps for conditioning a capillary column.

To Install a Capillary Column in the GCMSD Interface

Procedure for installing a capillary column into the GC/MSD interface.

Columns

Conditioning columns

To Prepare a Capillary Column for Installation

To Install a Capillary Column in a SplitSplitless Inlet

To Condition a Capillary Column

To Install a Capillary Column in the GCMSD Interface

3 Operating in Electron Impact (EI) Mode

Operating the MSD from the Data System

Operating the MSD from the LCP

LCP Menus

The EI GCMSD Interface

Before You Turn On the MSD

Checks to perform before powering on the MSD.

Pumping Down

Procedure for pumping down the MSD.

Venting the MSD

To Tune the MSD in EI Mode

To Verify System Performance

LCP Menus

The EI GCMSD Interface

Before You Turn On the MSD

Pumping Down

Controlling Temperatures

Controlling Column Flow

Venting the MSD

To Set Analyzer Temperatures from the Instrument Control View

To Set the GCMSD Interface Temperature from MassHunter

To Calibrate Column Flow Linear Velocity

To Tune the MSD in EI Mode

To Verify System Performance

To Vent the MSD

To Pump Down the MSD in EI Mode

To Set the Interface Temperature from the GC

4 Operating in Chemical Ionization (CI) Mode

General Guidelines

To Operate the CI MSD

To Switch from the EI Source to the CI Source

To Set Up Methane Reagent Gas Flow

CI Autotune

General Guidelines

The CI GCMSD Interface

To Operate the CI MSD

Start the system in PCI mode

To Switch from the EI Source to the CI Source

To Pump Down the MSD in CI Mode

To Set Up the Software for CI Operation

To Operate the Reagent Gas Flow Control Module

The flow control module

To Set Up Methane Reagent Gas Flow

To Switch from the CI Source to the EI Source

CI Autotune

To Perform a PCI Autotune (Methane Only)

To Perform an NCI Autotune (Methane Reagent Gas)

To Verify PCI Performance

To Verify NCI Performance

5 General Maintenance

Maintaining the Vacuum System

To Remove the EI Ion Source

To Clean the EI Source

To Replace a Filament in an EI Source

Tools, spare parts, and supplies

High voltage precautions

Warnings about dangerous voltages inside the MSD.

Dangerous temperatures

Electrostatic discharge

Maintaining the Vacuum System

Periodic maintenance

To Remove the EI Ion Source

To Clean the EI Source

To Replace a Filament in an EI Source

To Reinstall the EI Ion Source

To Replace the Electron Multiplier Horn

6 CI Maintenance

To Install the CI Ion Source

To Remove the CI Source

To Clean the CI Source

To Replace a Filament in a CI Source

Ion source cleaning

To Set Up Your MSD for CI Operation

To Install the CI Ion Source

To Install the CI Interface Tip Seal

To Remove the CI Source

To Clean the CI Source

To Replace a Filament in a CI Source