PlasmaQuant MS product family Detector calibration
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There are four attenuation mode settings available for any isotope in a method:
No attenuation
Medium
High
Auto
Each attenuation mode can be selected on a per mass basis and works best over
different concentration ranges for any given isotope. However, with iCRC the use of
attenuation modes is limited (see Summary 14).
Summary 14 Detector attenuation with and without iCRC
Auto attenuation Manual attenuation
without iCRC
with iCRC
possible attenuation modes:
no attenuation
medium attenuation
When manually choosing medium attenuation mode, the signal in the detector is
suppressed, so very low concentrations may not be detected at all. However, a greater
concentration of ions can be measured because the signal which may have over-
ranged in
NONE mode is suppressed by attenuation so that the counts reaching the end
of the detector are lower and can now be measured. Similar logic applies for high
attenuation mode.
Fig. 48 Linear dynamic range of different attenuation modes
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