Genevac Rocket 4D - Acceptable Solvents

Rocket 4D Evaporation System
User Manual
18 04-7848 Issue 2-4 August 2014
Acceptable solvents
The solvents listed in the following table will not damage the evaporator, providing
appropriate methods are used. Contact your local Genevac representative for advice
before using any solvent which is not listed.
Solvent
Recommended method
Acceptable?
Acetic acid
MeCO
2
H
Aqueous
■
Acetic anhydride
Medium BP
■
Acetonitrile
MeCN, ACN
Low BP
■
Amonium hydroxide
NH
3
OH
Requires special method
□
1-Butanol
Medium BP
■
2-Butanol
Medium BP
■
Butanone
MEK
Low BP
■
Butyl acetate
Medium BP
■
tert-Butyl alcohol
tert-butanol
Aqueous
■
Chlorobenzene
Medium BP
■
Chloroform
CHCl
3
Very Low BP
■
Cyclohexane
Low BP
■
1,2-Dichloroethane
DCE
Low BP
■
Dichloromethane
DCM
Very Low BP
■
Diisopropyl ether
DIPE
Low BP
■
N,N-Dimethyl formamide
DMF
Medium BP
■
1,4-Dioxane
Aqueous
■
Ethanol
EtOH
Low BP
■
Ethyl acetate
EtOAc
Low BP
■
Formic acid
HCO
2
H
Aqueous
■
Heptane
Low BP
■
Hexane
Low BP
■
Methanol
MeOH
Low BP
■
Methyl teriary butyl ether
MTBE
Low BP
■
1-Pentanol
Medium BP
■
Petroleum ether
pet ether
Low BP
■
1-Propanol
Low BP
■
2-Propanal
IPA, iso-propanol
Low BP
■
Propanone
Acetone
Low BP
■
Pyridine
Medium BP
■
Sodium hydroxide (aqueous)
NaOH
Aqueous
■
Tetrahydrofruoran
THF
Low BP
■
Toluene
Low BP
■
Triethylamine
Et
3
N
Low BP
■
Water
H
2
O
Aqueous
■
Water & Acetonitrile
HPLC
■
Water & Methanol
HPLC
■
Water & Ammonia
Requires special method
□
TFA & DCM
Low BP Mix
■
■
Solvent may be evaporated using Rocket
□
Requires special method

Before evaporating DMF, pre-heat the evaporator by running the Medium BP method
with no solvent for 15 minutes.