CHAPTER 5
88 PerkinElmer Life and Analytical Sciences
Static Controller
Mark this box to activate the instrument’s static-controlling device, which is
designed to reduce static originating on the sample vial. Static discharge can
falsely elevate sample counts by producing non-beta pulses. This device should be
activated in most cases. It’s default value is On. It is especially important in low
humidity conditions, when using plastic vials and when handling vials with latex
gloves. To further reduce the likelihood of generating static:
Maintain a relative humidity level above 40%.
Wipe latex gloves with anti-static wipes before handling vials.
Use the Pre-count delay timer. It delays the counting of each sample allowing
time for static-induced pulses to dissipate.
Note: The Static Controller can cause a decrease in the signal to
noise ratio in SPC Assays. Therefore, it is typically not used in this
assay type. It is especially important in SPC Assays to employ the
above mentioned techniques to minimize the likelihood of
generating static.
Luminescence Correction
Mark this box to activate luminescence correction. The instrument corrects the
data for counts resulting from sample luminescence. This feature is optional on
2800 and 2900 series instruments.
Colored Samples
Mark this box to activate color correction. The instrument will correct the data for
color quench. Typically, this is only required if samples are highly colored. Note:
This field will be enabled only for DPM Assays.
Heterogeneity Monitor
Mark this box to activate a device that monitors and flags heterogeneous samples
(such as samples with phase separation). This feature is not available on the
2800TR. It is optional on the 2900TR.
Note: This field will only be enabled for Single Label DPM Assays
where tSIE is selected as the Quench Indicating Parameter. The
system uses the tSIE and the sample spectrum endpoint to
determine sample heterogeneity.