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XCell Lab XC-LAB-S
REPLIGEN XCell Lab XC-LAB-S - User Manual
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1
XC
-
LAB
-
UG
-V4
XCell
™
L
ab Controlle
r
User
G
uide
•
PLC Soft
ware Versi
on
1.00
•
HMI Soft
ware Vers
ion
1.11
•
Surface P
ro
SP7
+
•
Windows Version
10 P
ro
20H2
•
Devices su
pported
XCell
ATF
® 1, 2 a
n
d 4
2
Table of Contents
Main Page
Table of Contents
3
Figure 1. Xcell™ Lab Controller and Accessories
9
Table 1. Explanation of User Attention Phrases
10
Table 2. Safety Precautions Examples
10
Table 3. Safety Warnings
11
Figure 2. ATF Pressure and Exhaust Strokes
14
Figure 3. Backflush Example
14
Figure 4. Configuration - Bioreactor, Controller, and Utilities
15
Table 4. Xcell™ Lab Controller Model Comparison
16
Figure 5. Face a of Controller
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Figure 6. Face B of Controller
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A2B and A2C Tubing Sets
18
Table 5. Controller Ports
18
Table 6. A2B Tubing ID/OD
19
Table 7. SAPA Components
19
Figure 7. SAPA Components Example
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Windows Environment
20
Repligen Xcell™ Lab Software
20
Modbus/Ethernet Remote Monitoring
20
Figure 8. Touchscreen Splash Display Example
21
Table 8. Preset Usernames and Passwords
22
Figure 9. Login Screen Example
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Figure 10. Overview/Scada Screen Example
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Menu Bar
24
Figure 11. Menu Bar Example
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Figure 12. User Information
24
Figure 13. ATF Main Screen Example Two Xcell ATF® Devices Attached to same Vessel
25
Figure 14. Example - 2 Synchronized Xcell ATF® Devices Attached to the same Bioreactor
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Figure 15. Example - 2 Xcell ATF® Devices Attached to Two Bioreactors
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Figure 16. Example - Dual Controller and Single Xcell ATF® Device
27
Figure 17. ATF Flow Pop-Up Example
27
Changing ATF Flow Set Points
28
Starting, Pausing and Stopping an Xcell ATF® Device
28
Pump Status Box
28
Table 9. Starting, Pausing and Stopping an Xcell ATF® Device Instructions
28
Figure 18. Xcell ATF® Device Status - Running, Paused or Stopped
28
Dual Mode
29
Table 10. Pump Status Messages Examples
29
Table 11. ATF Modes - Independent and Dual
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Figure 19. ATF DUAL Pop-Up Example
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Table 12. Starting, Pausing and Stopping Xcell ATF® Device(S) in Dual Mode
31
ATF Displacement Volume Pop-Up Window
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ATF Pressure Pop-Up Window
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Figure 20. ATF Displacement Volume Pop-Up Example
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Figure 21. ATF Pressure Pop-Up Screen Example
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Settings Sub-Menu
33
Xcell ATF® Device Configuration
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Figure 22. Settings Sub-Menu Example
33
Figure 23. Xcell ATF® Device Configuration Example
33
Bioreactor Configuration
34
Default Configuration/Atf Pump Settings
34
Figure 24. Bioreactor Configuration Example
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Figure 25. ATF Pump Settings Example
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General Configuration
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Figure 26. General Configuration Example
35
Service /Performance Screen
36
Logon Required - Security On/Off
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Table 13. ATF Service Parameters
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Figure 27. Service/Performance Example
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Algorithm Pop-Ups
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Figure 28. ATF-A Algorithm Pop-Up Example
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Figure 29. ATF-A and ATF-B Algorithm Pop-Ups
37
Xcell™ Lab Trend Screen
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Figure 30. Xcell™ Lab Trend Screen Example
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Figure 31. Alarm Condition Example
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Figure 32. Alarm Status
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Alarm Configuration
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ATF Flow Alarm Configuration
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Table 14. Alarm Status
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Figure 33. Alarm Configuration Example
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Displacement Volume Alarm Configuration
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System Alarm Configuration
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Figure 34. Displacement Volume Alarm Example
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Figure 35. System Alarms Example
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Permeate (P3) Pressure Alarm Configuration
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Figure 36. P3 Permeate Pressure Alarm Example
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Historian Client Software
43
Trend
43
Figure 37. Accessing Trend and Query Example
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Figure 38. Trend Screen Example
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Query Tool
44
Exporting Data to Excel
44
Figure 39. Query Example
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Figure 40. Columns Pane - Subset of the Query Window
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Figure 41. Query Set-Up
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Figure 42. Help Feature
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Figure 43. Workflow for a Typical ATF Start-Up Process
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Table 15. Recommended ATF Rate to Filtration Rate Ratios
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Table 16. Xcell™ Lab System Price and Parts List - for Sales
51
Figure 44. Control Panel Network and Sharing Center
56
Figure 45. Control Panel's Network Adapter Properties
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Figure 46. Windows 10 Network Adapter Tcp/Ipv4 Properties
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Table 17. Windows Usernames and Passwords
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Table 18. Xcell™ Lab Users and Roles
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Changing Usernames and Passwords
61
Figure 47. Default Values for ATF Pump Configuration
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Figure 48. Default Values for ATF Flow Alarms
66
Figure 49. Default Values for Displacement Volume Alarms
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Figure 50. Default Values for System Alarms
67
Figure 51. Default Values for P3 Permeate Pressure Alarms
68
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REPLIGEN XCell Lab XC-LAB-S Specifications
General
Brand
REPLIGEN
Model
XCell Lab XC-LAB-S
Category
Controller
Language
English
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