REPLIGEN XCell Lab XC-LAB-S - Page 5

KrosFlo® TFDF™ Lab System
User Guide
XCell™ Lab Controller
User Guide
5
XC-LAB-UG-V4
List of tables
Table 1. Explanation of user attention phrases ................................................................................ 10
Table 2. Safety precautions examples .............................................................................................. 10
Table 3. Safety warnings ................................................................................................................... 11
Table 4. XCell™ Lab Controller model comparison .......................................................................... 16
Table 5. Controller ports................................................................................................................... 18
Table 6. A2B Tubing ID/OD ............................................................................................................... 19
Table 7. SAPA components ............................................................................................................... 19
Table 8. Preset usernames and passwords ...................................................................................... 22
Table 9. Starting, pausing and stopping an XCell ATF® Device instructions ..................................... 28
Table 10. Pump status messages examples ....................................................................................... 29
Table 11. ATF modes - independent and dual ................................................................................... 30
Table 12. Starting, pausing and stopping XCell ATF® Device(s) in Dual Mode ................................... 31
Table 13. ATF service parameters ...................................................................................................... 36
Table 14. Alarm status ........................................................................................................................ 40
Table 15. Recommended ATF rate to Filtration rate ratios ............................................................... 48
Table 16. XCell™ Lab System Price and Parts List - for Sales .............................................................. 51
Table 17. Windows usernames and passwords ................................................................................. 60
Table 18. XCell™ Lab users and roles ................................................................................................. 60
List of figures
Figure 1. XCell™ Lab Controller and accessories ................................................................................ 9
Figure 2. ATF pressure and exhaust strokes ..................................................................................... 14
Figure 3. Backflush example ............................................................................................................. 14
Figure 4. Configuration - bioreactor, controller, and utilities .......................................................... 15
Figure 5. Face A of Controller ........................................................................................................... 17
Figure 6. Face B of Controller ........................................................................................................... 17
Figure 7. SAPA components example ............................................................................................... 19
Figure 8. Touchscreen splash display example ................................................................................ 21
Figure 9. Login screen example ........................................................................................................ 22
Figure 10. Overview/SCADA screen example ..................................................................................... 22
Figure 11. Menu bar example ............................................................................................................ 24
Figure 12. User information ............................................................................................................... 24
Figure 13. ATF main screen example two XCell ATF® Devices attached to same vessel ................... 25
Figure 14. Example - 2 synchronized XCell ATF® Devices attached to the same bioreactor ............. 26
Figure 15. Example - 2 XCell ATF® Devices attached to two bioreactors ........................................... 26
Figure 16. Example - Dual controller and single XCell ATF® Device ................................................... 27
Figure 17. ATF Flow pop-up example ................................................................................................. 27
Figure 18. XCell ATF® Device status - running, paused or stopped .................................................... 28
Figure 19. ATF DUAL Pop-up example ................................................................................................ 30
Figure 20. ATF displacement volume pop-up example ...................................................................... 32
Figure 21. ATF pressure pop-up screen example ............................................................................... 32
Figure 22. Settings sub-menu example .............................................................................................. 33
Figure 23. XCell ATF® Device configuration example ......................................................................... 33
Figure 24. Bioreactor configuration example..................................................................................... 34
Figure 25. ATF pump settings example .............................................................................................. 34
Figure 26. General configuration example ......................................................................................... 35
Figure 27. Service/performance example .......................................................................................... 36
Figure 28. ATF-A Algorithm pop-up example ..................................................................................... 37
Figure 29. ATF-A and ATF-B algorithm pop-ups ................................................................................. 37
Figure 30. XCell™ Lab Trend screen example ..................................................................................... 38
Figure 31. Alarm condition example .................................................................................................. 39