Roche Diagnostics
E-8 Operator’s Manual · Version 3.1
12 ISE description Cedex Bio System
Overview
ISE solutions
The ISE unit requires several specific solutions for performing the analyses and
maintaining the system. They are listed in the following table.
Solution summary
Fluid stability For information on the stability of fluids see the package insert of the fluid in
question.
Solution Location Use
ISE Solution 1 Sample area Used in the two-point calibration of sodium and potas-
sium.
ISE Solution 2 Sample area Used in the two-point calibration of sodium and potas-
sium.
ISE Calibrator
Indirect
ISE unit Used in the one-point calibration after each measure-
ment. It is also used during ISE initialization and
standby, and for maintenance purposes.
ISE Reference
Solution
ISE unit Used in all ISE measurements of sodium, potassium,
and chloride.
Also used during ISE standby.
ISE Etcher Sample area Used as a cleaning solution for cleaning the ISE Sodium
Electrode during ISE maintenance.
ISE
Deproteinizer
Sample area Used as a cleaning solution for cleaning the probe, ion-
selective electrodes, ISE tower, and tubing during ISE
maintenance.
Activator Sample area Activates the electrodes, tubing, and the ISE tower dur-
ing ISE maintenance. It is also used for the initialization
of the ISE unit and for activating the probe.
Roche recommend using their Activator on the
Cedex Bio instrument. (For details see the package
insert of the Activator.)
Water External water
container
Used for diluting the samples, controls, and standard
solutions, and for cleaning purposes. It is also used dur-
ing ISE initialization.
Sample Sample area Sample tubes are placed on the sample area of the main
instrument and pipetted by the main instrument probe.
Waste Internal waste
tank
The waste is first pumped into the internal waste tank
of the main instrument and then to the external waste
container.
Table E-1 Solutions used with ISE analysis
Incorrect results due to changes in fluids
The chemical composition of ISE fluids changes over time. The assigned on-board stability
is the interval within which the quality of the fluid remains within the prescribed tolerances.
Using fluids whose interval has expired may lead to incorrect results.
Always exchange the fluids when an interval has expired. Follow the instructions given on
the screen.
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