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41 Introduction ..........................................................................................................

51.1 About this manual ................................................................................................................................

61.2 Important user information .............................................................................................................

81.3 Regulatory information ......................................................................................................................

91.3.1 EU Directives ....................................................................................................................................

101.3.2 Eurasian Customs Union ............................................................................................................

111.3.3 Regulations for USA and Canada ...........................................................................................

121.3.4 Korean regulatory information ................................................................................................

131.3.5 Other regulations and standards ............................................................................................

151.4 Associated documentation ..............................................................................................................

162 Safety instructions ...............................................................................................

172.1 Safety precautions ...............................................................................................................................

232.2 Labels .........................................................................................................................................................

262.3 Emergency procedures ......................................................................................................................

282.4 Recycling information .........................................................................................................................

292.5 Declaration of Hazardous Substances (DoHS) ........................................................................

313 System description ..............................................................................................

323.1 Biacore X100 instrument ..................................................................................................................

363.2 Indicators and switches ....................................................................................................................

373.3 Sensor chip ..............................................................................................................................................

383.4 Control system .......................................................................................................................................

394 Installation ............................................................................................................

404.1 Site requirements ..................................................................................................................................

434.2 Unpacking, assembly and transport ...........................................................................................

444.3 Connections ............................................................................................................................................

465 Operation ..............................................................................................................

495.1 Overview ...................................................................................................................................................

505.2 Starting the instrument ......................................................................................................................

535.3 Preparing, loading and changing buffers .................................................................................

545.4 Inserting a sensor chip .......................................................................................................................

565.5 Setting the analysis temperature ..................................................................................................

575.6 Preparing and loading samples and reagents .......................................................................

595.7 Starting a run ..........................................................................................................................................

605.8 Post-run procedures ...........................................................................................................................

616 Maintenance .........................................................................................................

636.1 Maintenance preparations ...............................................................................................................

656.2 Maintenance summary ......................................................................................................................

666.3 Cleaning ....................................................................................................................................................

706.4 Component maintenance ................................................................................................................

2 Biacore X100 Operating Instructions 28961142 AD

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