10  Virtual Touch  Applications 
10 - 14  Instructions for Use 
Shear Wave Velocity and Elasticity Measurements in Liver Assessment 
Virtual Touch quantification can provide a reliable measure of shear wave velocity and elasticity 
in the liver when proper technique is used.  
The following factors can result in abnormally high values in the liver: 
  Excessive transducer pressure on the liver, such as in subcostal scanning where 
transducer pressure is used to displace intervening bowel gas  
  Elevated central venous pressure due to heart failure or valsalva maneuvers (including 
deep inspiration and breath hold)  
  Significant portal hypertension 
  Poor contact with the skin surface or oblique transducer angles relative to the liver 
  Elevated aminotransferase levels  
  Food intake less than 2 to 3 hours prior to examination 
  Liver location (liver segment measured) 
  Liver fibrosis 
The following techniques should be used in liver assessment to ensure measurements using 
Virtual Touch quantification in liver assessment are reliable: 
  Measurements are most reliable at least 1 cm to 2 cm deep to the liver capsule using the 
intercostal scanning approach along a mid-axial line in liver segments 5 and/or 8. 
  The patient should breathe normally with measurements taken after the patient is asked to 
momentarily suspend respiration. 
  Multiple measurements in the same location should be taken to ensure measurement 
repeatability with the median shear wave velocity and elasticity value representing the 
most reliable single measure when there are measurement outliers. 
  The Virtual Touch quantification measurement region of interest (ROI) should be 
maintained between 3 cm and 6 cm depth whenever possible to minimize the effect of 
depth on measurements. Values can be higher at depths less than 3 cm and lower at 
depths greater than 6 cm.  
  An IQR/median shear wave velocity and elasticity ratio less than 0.3 is indicative of reliable 
liver assessment with Virtual Touch quantification. A higher ratio indicates significant 
variability in the measurements, decreasing the reliability of measurement results.