Agilent InfinityLab LC Series Diode Array Detectors User Manual 75
5 Optimizing the Detector
Introduction 76
Optimization Overview 77
Choosing a Flow Cell 78
Inline Pressure Relief Valve Kit (G4212-68001) 81
Application Information 81
Special Information of 60 mm Cartridge Flow Cell 81
Optimizing for Sensitivity, Selectivity, Linearity and Dispersion 83
Flow Cell Path Length 83
Peak width (response time) 85
Sample and Reference Wavelength and Bandwidth 87
Slit Width (G7117B) 90
Optimizing Spectral Acquisition 92
Margin for Negative Absorbance 93
Optimizing Selectivity 94
Quantifying Coeluting Peaks by Peak Suppression 94
Optimizing the Detector Regarding to the System 96
Delay Volume and Extra-Column Volume 96
How to Configure the Optimum Delay Volume 96
How to Achieve Higher Sensitivity 97
Warm up of the Detector 102
This chapter provides information on how to optimize the detector.