Roche Diagnostics
Operator’s Manual · Version 3.1 A-25
Cedex Bio System 2 Introduction to the instrument
Daily operation
You can work with up to eight different reagent disks on one Cedex Bio instrument.
You always load and remove bottles while the disk is on the instrument. (The system
needs to know exactly what is loaded on the disk.)
When you finished running tests, you can remove the whole reagent disk, place it in a
reagent disk container, and store it in a refrigerator.
Bottles Cedex Bio reagents, diluents and extra cleaners are provided in uniform bottles. They
are supplied with two dimensional barcodes and placed on the reagent disk with their
cap removed.
Chimneys Chimneys are bottle inserts that reduce evaporation. For reagents that are especially
sensitive to concentration changes, Roche recommend using chimneys on the
reagent bottles.
To generally reduce evaporation, you may use chimneys on all reagent bottles.
Reagent set Up to three reagents can be required to perform a certain test. These reagents are
handled in reagent sets. You can define more than one reagent set for a test, but only
one can be active.
A reagent set is defined as soon as its first bottle is loaded. From this moment on,
whenever you remove or replace a reagent, you do so for all reagents of the set.
Each diluent or cleaner bottle is treated as a separate reagent set.
Volume detection For each reagent set, the number of available tests is continuously calculated.
Periodic mixing Reagents may have a mixing interval defined. This interval is checked by the system
every 30 minutes, and mixing is performed without removing the reagent bottles
from the reagent disk.
For a reagent set that contains more than one reagent for which mixing is defined, the
shortest interval of all reagents of the set is used for all reagents.
Tests are blocked if any reagent they use requires mixing.
Diluents Both, system water and dedicated diluents are used. System water is kept in the
external water container, dedicated diluents are supplied in reagent bottles and
placed on the reagent disk.
Cleaners Both, a system cleaner and dedicated cleaners can be used. The system cleaner is kept
in the external cleaner bottle, dedicated cleaners are supplied in reagent bottles and
placed on the reagent disk.
Figure A-5 Remaining tests indication
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