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Cedex HiRes
Roche Cedex HiRes User Manual
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Table of Contents
Table of Contents
9
Contact Addresses
15
Prologue
15
Revision History
15
Copyrights
16
Declaration of Conformity
16
Intended Use
16
VIII. Software License Agreement
17
Trademarks
16
Warranty
16
Contents of this Operator's Guide
20
Conventions Used in this Guide
20
Preamble
20
FCC Notifi Cation
21
XIII. Warnings and Precautions
22
XIV. Disposal of the Analyzer
23
A Overview
25
Description of the Cedex Hires System
26
The Measurement Procedure
27
Data Analysis
28
Technical Specifi Cations of the Analyzer
29
B System Description
31
Installing the Cedex Hires System
31
Choosing a Suitable Location
32
Connecting or Disconnecting the Device
32
Connecting Hardware Components
33
Completing the Windows Mini-Setup
33
Installing Cedex Hires Software 2.2 or Updating to Cedex Hires Software 2.2
34
Installing the Cedex Hires Software 2.2
34
Setting the Cedex Server to Autostart
38
Starting up the Software
39
Updating Older Cedex Hires Software Version 2.X to Cedex Hires Software 2.2
40
Overview
40
Updating to Cedex Hires Software 2.2
40
Restoring a Cedex Hires Software 2 Backup
43
Starting the Cedex Hires System after Installation
45
Securing Access Rights
46
Access Control at the Windows Operating System Level
46
Access Control at the Cedex Hires System Software Level
46
C Operation
47
Overview of the Cedex Control Center
47
Menu Bar
47
System Menu
47
Measurement Menu
48
Functions Menu
48
Reports Menu
49
Master Data Menu
49
Setup Menu
49
Help Menu
50
Shortcut Area
50
Tracking of Status of Events Carried out by the Analyzer
50
Preparing the Analyzer for Measurements
51
Switching on
51
Logging in at the Computer Operating System Level
51
Starting the Cedex Hires Software 2.2
51
Performing a HW Startup and Prime
52
Preparing the Reagent Kit
53
Installing or Changing the Reagent Kit
53
Refi Lling Containers Individually
54
Checking the Analyzer
55
Carrying out a Single Measurement
56
Opening the Measurement Window and Specifying the Operating Mode and Sample Data
57
Defi Ning the Measurement and Analysis (Process) Parameters
58
Preparing the Sample and Attaching It to the Multi Sample Tray or Sample Port
59
Starting the Measurement
59
End of Measurement
60
Interrupting a Measurement
61
Working with the Multi Sampler
62
The Multi Sampler Defaultcup
63
Preparing the Measurement
64
Using the Multi Sample Tray
64
Ejecting the Multi Sample Tray
64
Performing a Prime
65
Carrying out Measurements with the Multi Sampler
65
The Multi Run Data Entry Window
65
Preparing for Multiple Measurements in the Multi Run Window
65
Activating Sample Rows and Starting the Measurement
66
Adding Measurements to the List While Measurements Are Running
68
Modifying Data Entry, Changing Samples
69
Non-Linear Measurements in a Sample Series
69
Interrupting a Multi Run
69
Disruption of Measurements
69
Results
70
The Multi Run Result List
70
Switching off the Cedex Hires Analyzer
71
Carrying out an LM Shutdown and HW Shutdown
71
Logging out
72
Shutting down the Control Center
72
Software
73
Using the Measurement Results Window
73
Result Data Area
74
Sample Parameters and Processing Parameters Areas
75
Image Area
76
Viewing Individual Cell Images
76
Viewing a Cell Image Using the Image View Window
77
Excluding Images from the Evaluation Process/Including Excluded Images
78
Viewing the Prescan Image
79
Using the Measurement List
80
Viewing Analysis Results
81
Searching for Measurements
81
Editing Existing Analysis Results/Data Sets
82
The Reprocess Button
82
Effective Data Sets
83
Graphical Display of the Analysis Results
84
Enlarging the Histograms
84
Aggregate Histogram
85
Cell Diameter Histogram
87
Object Diameter Histogram
88
Defi Ning Diameter Intervals in the Diameter Histograms
88
Compactness Histogram
89
Measurement Statistics Histogram
90
Cultivation Time Chart
91
Creating a CTC View
91
The View Area
92
The Series of Measurements Belonging to Selected View Area
92
Adding Measurements to a View
93
Editing Measurements in a View
94
Viewing List of Measurements in a Series
94
Deleting Views and Series
95
Exporting a View
95
Creating a Cultivation Time Chart
95
The Data Selection Area
96
Fitting to the Lowest Common Value
97
Measurement Series Offset
97
Variable Axis Calibration
97
The Exponential Regression Button
98
Printing out a Cultivation Time Chart
98
General Functions of the System
99
Data Management
99
Printing Reports
99
Export to Fi Le
100
Data Exchange
101
Export
101
Import
102
Viewing and Evaluating the Audit Trail File
102
User Preferences
103
Adjusting Result Display in the Measurement List and Multi Run Windows
103
Specifying Default Measurement Parameters
104
Specifying Other Default Parameters
104
Specifying the Workarea for the Analysis Data
105
Changing Own Password
105
Administrator Functions
106
Administration of User Accounts
106
Creating User Accounts
106
Assigning Access Rights
107
Creating User Groups
108
Editing and Deleting User Accounts
108
Creating and Editing User Roles
109
Password Management
110
Specifying Password Characteristics
110
Assigning New Passwords
111
Assigning Work Areas
111
The System Options
112
Automatically Start the Hardware Management
112
Modifying the Standard Setting for the Multi Sampler Defaultcup
113
Turning off Automatic Incrementation of Sample Cup Position
113
Turning off the Flow Chamber Prescan
114
Error Level Displayed to Users
115
Liquid Container Confi Guration
115
Disabling the Reagent Control
115
Default Settings
115
Adjustment of the Image Analysis Using the Live Operator
116
Description of the Cell Type List and Live Operator
117
The Cell Type List Window
117
Creating a New Cell Type
118
Editing an Existing Cell Type
119
Viewing an Existing Cell Type
119
Deleting an Existing Cell Type
120
Working with the Live Operator
121
Description of the Individual Operator Parameters
123
Archiving Data
125
Archive
125
Restore
126
Deleting Archived Data
126
Cleaning and Maintenance Check List
127
E Maintenance and Care
127
Scheduling Automatic Cleaning Routines
128
Daily and Manual Maintenance and Cleaning Routines
129
Checking the Reagent Containers When Manually Refi Lling
129
Cleaning Routines Carried out by the Liquid Management
130
Cleaning Options
130
The Hardware Management Window
132
Carrying out a Cleaning Routine
132
Interrupting/Terminating a Cleaning Routine
132
Scanning the Chamber to Verify the Effectiveness of Cleaning Routines
132
Automatic Adjustment and Alignment Verifi Cation
134
Syringe Maintenance
136
Removing the Syringe
136
Assembling and Installing the Syringe
137
Maintenance of the Syringe Guide and Spindle
138
Maintenance of the Flow Chamber, 8-Way Valve and the Remaining Hardware Components
139
Operational Data
139
The System Suitability Test (SST)
140
Creating SST Checkpoints
140
Creating SST Checkpoints with and Without Measurements
140
Running a Water Blank
142
Setting up the Sstfailurereaction in the System Options Menu
142
Performing an SST
143
Performing an SST with Measurements
143
Performing an SST Without Measurements
144
Tracking Trends in SST Results over Time
145
Tracking Trends in SST Checkpoints with Measurements
145
Tracking SST Checkpoints Without Measurements
147
Locking - Unlocking the System
148
Diagnosis of the Cedex Hires Analyzer
149
F Troubleshooting
149
The System Audit Trail File
150
Trace and Logging
150
G Appendix
151
System Options und User Preferences
151
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Roche Cedex HiRes Specifications
General
Manufacturer
Roche
Model
Cedex HiRes
Operating Temperature
15-30°C
Power Requirements
100-240 V, 50/60 Hz
Operating Humidity
20-80%
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