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Diagnostics and Troubleshooting
Replacing Fuses
130 TSQ Quantum XLS Series User Guide Thermo Scientific
Issue: Weak signal. Possible causes/solutions
• The ion volume or ion source lenses are dirty. Clean the contaminated components as
described in “Cleaning Ion Source Components” on page 85.
• The multiplier is set too low. Run multiplier gain calibration in the tune and calibration
procedure as described in “Tuning and Calibrating” on page 61. An electron multiplier
older than 2–3 years may be too noisy for the multiplier gain calibration to accurately set
the voltage. You might need to replace the electron multiplier. Contact Thermo Fisher
Scientific Technical Support.
• The wrong type of ion volume is installed. EI and CI require different ion volumes. They
may not be used interchangeably. Change the ion volume as described in “Changing
Ionization Modes” on page 73.
• The ion volume is absent or incorrectly positioned. Verify that the ion volume is
positioned correctly.
• There is a filament or lens control problem. See “Filament and Lens Control Issues” on
page 119 for more information.
• The electron multiplier is faulty. Contact Thermo Fisher Scientific Technical Support.
Replacing Fuses
Replacing PCBs and Power Supplies
CAUTION Fuses protect the various circuits by opening the circuits whenever overcurrent
occurs. On the TSQ Quantum XLS Series mass spectrometers, a failed fuse indicates a
failed board or electronic module that must be replaced by a Thermo Fisher Scientific
field service engineer.
CAUTION The TSQ Quantum XLS Series mass spectrometer electronic assemblies are
close packed to minimize the size of the system. Due to the complexity of removing and
reinstalling the mass spectrometer electronic assemblies, only a Thermo Fisher Scientific
field service engineer can replace electronic assemblies.
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