Contents
Introduction
About the Instrument 1
Common Abbreviations and Units 1
How To Obtain Support
Applications Support 2
Technical Support 2
Requested Information 2
CEM Corporation Headquarters 2
CEM International Subsidiaries 3
Safety
Safety Notations 5
Personal Laboratory Safety 5
Waste Disposal 5
Fume Ventilation 5
Operating Precautions 6
System Requirements
Bench and/or Fume Hood Space 7
System Components Space Requirements 7
Environmental Conditions 7
Inert Gas Source 7
Electrical Requirements 7
Fuse Replacement 7
Introduction To The Liberty Blue
Components and Parts 8
Quick Setup Guide
Create and Load the Liberty Method 10
Prepare and Load Reagents 11
Run the Method 12
Operation of the Liberty Blue
Software Terminology 14
Liberty Blue Software Main Screen 14
Microwave Editor 16
Cycle Editor 18
Liberty Method Editor 22
Calculators 28
Edit Users and User Group 30
Setting up a Synthesis
Loading a Method 33
Standard Reagents and Concentrations 33
Recommended Reagents and Strategies for Microwave
SPPS on the Liberty Blue 33
Preparing Reagents 36
Setting up the Liberty Blue 37
Running the Liberty Blue 39
Generating A Run History Report 40
Cleavage 40
Maintenance of the Liberty Blue
Recommended Routine Maintenance Schedule 42
Maintenance Procedures 43
Maintenance Screen 47
Using the Change Bottle Operations 47
Calibration Screen 48
Advanced Features
Cycle Rules 50
Reagent Library 50
Bottle Setup 52
Rell Reagents Button 53
Diagnostics Screen 53
Settings Screen 53
Reaction Vessel Camera Option 54
Warranty
Limited Warranty Information 55