Gilson 333 - Page 57

Hydraulic Problems
Problem Possible Causes Solutions
Air bubbles in both the inlet
and the outlet tubings
Inlet tubing is loose
Nut and/or ferrule damaged
Tighten the connectors
Replace the nut and/or ferrule
Inlet filter is plugged
Clean or replace the inlet
filter(s)
Refill time is too short
Increase the refill time; refer to
page 37
Air bubbles in the outlet tubing
only
Loose connection of outlet Tighten connectors
Leaks from a pump head Defective piston seal Replace the defective seal
Abnormally low flow rate
Leaks
Check the all plumbing for
leaks
Air entering upstream from the
head
Check the upstream
connections
Plugged inlet filter Replace inlet filter
Defective check valve
Clean or replace the check
valve
Incorrectly mounted pump
head
Remount the pump head
Abnormally high pressure
Plugged outlet filter Clean or replace outlet filter
Column particle size too small
or plugged column
Change or flush column
Mobile phase viscosity too high
Use lower viscosity solvents or
increase temperature
Baseline noise, periodic pulses
Mixer volume too small Increase mixer volume
Air in the hydraulics
Prime the pump, degas the
solvent
Faulty pressure module
Contact your Gilson
representative
NOTE
Contact your local Gilson representative or techsupport@gilson.com for assistance resolving
problems described in this chapter.
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