Ca-2 Operator’s Manual – OPTI CCA-TS2
CALCIUM ANALYTES
Measurement Range
Range Resolution (Low/High) Units
0.2 to 3.0 0.01 mmol/L
Standard Reference Cassette (SRC) Limit Values
LOW NORMAL HIGH Units
1.8 ± 0.1 1.1 ± 0.1 0.7 ± 0.1 mmol/L
Interferences
The OPTI CCA Ca
++
sensor does exhibit an interference from bisulfate and phenylacetic acid.
Heparin salts are the only acceptable anticoagulants. Other anticoagulants such as citrate, EDTA, oxalate,
and uoride cause signicant interferences to the electrolyte sensors.
The following exogenous interferents were quantied in tonometered plasma, showing interferences to
dyes which typically have short half-lives within the body before being metabolized by the liver.
This testing was done on the OPTI CCA platform, with a standard OPTI style Ionized Calcium sensor.
No changes were made to the sensor or the measurement principle, so the interference of the OPTI CCA-
TS2 is equivalent to the OPTI CCA.
Substance Amount Ca
++
change (mmol/L)
Sodium uorescein 26 mg/dL unstable
Cardio (indocyanine) green 0.5 mg/dL +0.1
Methylene blue 25 mg/dL unstable
Only clear, uncolored quality control materials, such as OPTI CHECK or OPTI CHECK PLUS brand
aqueous controls should be used with the OPTI CCA-TS2 system. Colored materials, including
prociency testing materials, may interfere with the ionized calcium measurement, or fail to be properly
aspirated.