Section G – Dissolution Testing
CD14 Tester & CD AutoPlus Autosampler User Guide—75-108-800 Rev. B—31 May 2021 95 of 130
EAR99 technology subject to restrictions on cover page.
6. Prepare the dosage:
a. Baskets
i. Place the dosage in each of the baskets and
install the baskets on the basket shafts.
ii. Lower the drive head to the testing position
with all spindle shafts pulled up, taking care
that the baskets do not come into contact
with the vessel covers.
iii. Remove the cover over position 1.
iv. Lower the basket on position 1 to the testing
position and start the test.
v. Replace the vessel cover over position 1.
vi. Repeat the previous steps for the remaining
positions in turn, based on the desired
stagger time.
b. Paddles
i. Drop the dosage into vessel 1 by lifting up
the side of the vessel cover and inserting
the dosage through the opening into the
vessel while grasping the spindle clamp, so
the paddle does not spin.
ii. Push the paddle down into the testing
position and start the test.
iii. Replace the vessel cover over position 1.
iv. Repeat the previous steps for each of the
remaining positions in turn, based on the
desired stagger time.
c. Paddles with ADD cover
i. Place the dosage in each of the dose tubes
located on the ADD cover for all positions.
ii. Place the dose caps on top of the dose
tubes for all positions.
iii. Drop the dosage into position 1 by
depressing the push pin.
iv. Start the test.
To Next Page
Loading...
