Waters ACQUITY - Page 46

Figure 3–12: Cleaning the ion guide
Ion guide
2. Add Waters MS Cleaning Solution or 1:1 methanol/water to the glass vessel until the ion
guide is immersed completely.
3. Place the vessel containing the ion guide in the ultrasonic bath for 20 minutes.
4. Carefully pour the cleaning solution from the vessel holding the ion guide into the holding
container, retaining the ion guide in the vessel.
Tip: You can reuse Waters MS Cleaning Solution for one subsequent cleaning.
5. Fill the vessel with deionized water to rinse the ion guide, and then discard the water.
6. Refill the vessel with deionized water to rinse the ion guide a second time, and then
discard the water.
7. Fill the vessel with isopropyl alcohol, ensuring that the ion guide is immersed completely.
8. Place the vessel containing the ion guide in the ultrasonic bath for 20 minutes.
9. Carefully remove the ion guide from its vessel and blow-dry the component using inert, oil-
free gas.
10. Discard the used isopropyl alcohol using an appropriate waste container.
June 15, 2017, 715003956 Rev. F
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