Symbol Definition
Electrical and electronic equipment with this symbol may contain
hazardous substances and should not be disposed of as general waste.
For compliance with the Waste Electrical and Electronic Equipment
Directive (WEEE) 2012/19/EU, contact Waters Corporation for the correct
disposal and recycling instructions.
Serial number
Part number, catalog number
Audience and purpose
This guide is for novice users and assumes no knowledge of liquid chromatography or mass
spectrometry principles. It provides an overview of the instrument and explains how to install it,
prepare it for operation, and maintain it.
Intended use of the ACQUITY QDa detector
Waters designed the ACQUITY QDa detector for use as an ion confirmation and quantitation tool,
as part of an ACQUITY UPLC or UPC² system, Alliance, and LC and SFC prep systems. The
ACQUITY QDa detector is not intended for use in diagnostic applications.
Calibrating
To calibrate LC systems, adopt acceptable calibration methods using at least five standards to
generate a standard curve. The concentration range for standards must include the entire range
of QC samples, typical specimens, and atypical specimens.
Quality control
Routinely run three QC samples that represent subnormal, normal, and above-normal levels of a
compound. If sample trays are the same or very similar, vary the location of the QC samples in
the trays. Ensure that QC sample results fall within an acceptable range, and evaluate precision
from day to day and run to run. Data collected when QC samples are out of range might not be
valid. Do not report these data until you are certain that the instrument performs satisfactorily.
June 15, 2017, 715003956 Rev. F
Page viii
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