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Waters ACQUITY - Replacing the Entrance-Aperture Seal and Disc; Removing the Ion Block

Waters ACQUITY
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Entrance-aperture carrier
Disc aperture assembly
Sample cone
3.8.2 Replacing the entrance-aperture seal and disc
Replace the entrance seal aperture when these conditions apply:
You have dismissed LC and sample-related causes for decreased signal intensity.
Cleaning the source components fails to increase signal stability.
Required materials
New entrance-aperture seal and entrance-aperture disc
Chemical-resistant, powder-free gloves
Warning: To avoid personal contamination with biohazardous or toxic compounds, wear clean,
chemical-resistant, powder-free gloves when performing this procedure.
To replace the entrance-aperture seal:
1. Dispose of the old entrance-aperture seal and disc according to your local environmental
regulations.
2. Insert the new entrance-aperture seal and disc into the sample cone.
Requirement: The Standard and Performance QDa Detectors require different entrance
aperture discs. When ordering a replacement entrance-aperture disc and seal, ensure that
the entrance-aperture disc is the correct type.
3. Refit the source components (see Refitting the source components).
3.8.3
Removing the ion block
Clean the ion block when cleaning the sample cone assembly fails to increase signal sensitivity.
Required materials
Chemical-resistant, powder-free gloves
2.5-mm hex wrench
June 15, 2017, 715003956 Rev. F
Page 34

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