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Waters ACQUITY - Cleaning the Instrument Case; Cleaning the Ion Guide Assembly

Waters ACQUITY
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1. If you removed the O-rings from the source components, refit them.
2. Insert the rubber entrance-aperture seal into the sample cone.
3. Insert the entrance-aperture carrier into the sample cone assembly.
Note: Ensure that the entrance aperture seal is in place in the entrance-aperture carrier.
4. Insert the entrance-aperture carrier and sample cone assembly into the entrance-aperture
on the right-hand side of the ion block.
5. Insert the calibration pin into the top of the ion block.
6. Place the ion block assembly against the ion block support on the front of the instrument,
aligning the screw positions.
7. Secure the ion block to the instrument using the two 3-mm screws and tighten them using
the 2.5-mm hex wrench.
8. Refit the source enclosure (see Fitting the source enclosure to the instrument).
3.9 Cleaning the instrument case
Notice: To avoid abrading the surfaces of the instrument, do not use abrasives or
solvents when cleaning them.
Use a soft cloth, dampened with water, to clean the outside surfaces of the mass spectrometer.
3.10
Cleaning the ion guide assembly
Clean the ion guide assembly when these conditions apply:
You have dismissed LC and sample-related causes for decreased signal intensity.
Cleaning the source components fails to increase signal stability.
Replacing the entrance-aperture seal and disc fails to increase signal stability.
3.10.1
Removing the ion guide assembly from the source assembly
Required material:
Chemical-resistant, powder-free gloves
3-mm hex wrench
2.5-mm hex wrench
Flat-blade screwdriver
June 15, 2017, 715003956 Rev. F
Page 39

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