3030226 Rev. D 3-7 System Operation
3.3 Disinfection Indications
DETERMINATION OF MICROBIAL CULTURING AND DISINFECTION FREQUENCY IS THE
RESPONSIBILITY OF THE OPERATING FACILITY. The following is recommended for
critical applications where bacteria and endotoxins are a major concern, such as for
Hemodialysis.
Disinfection should occur when bacterial growth is above the limits set by the facility or
when within 50% of the maximum allowable level. Routine disinfection at lower CFU
counts will inhibit colonization of bacteria in the system and the distribution plumbing.
Rapid re-growth of bacteria following disinfection or excessively high colony counts, i.e.,
TNTC, may indicate a need for more aggressive intervention. Strategies such as
increased frequency of disinfection/sanitization may be employed.
NOTE:
At a minimum, cultures should be taken prior to disinfection. To determine
effectiveness, cultures can be taken pre and post disinfection.
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