Glu-2 Operator’s Manual – OPTI CCA-TS2
GLUCOSE ANALYTES
Measurement Principle
The glucose optode measurement is based on the enzymatic oxidation of glucose.
Glucose + O
2
gluconic acid + H
2
O
2
glucose oxidase
The sensor is constructed of an enzyme layer over an oxygen sensor. As a sample containing glucose
contacts the sensor
, the oxidation of the glucose consumes the oxygen locally present in the sensor.
This decrease in oxygen is detected in the same manner (luminescence quenching) as described for the
PO
2
optode. The amount of glucose is determined to be proportional to the rate at which the oxygen is
consumed.
Measurement Range
Range Resolution (Low/High) Units
30 to 400
(70 to 400 mg/dL for samples with
pO
2
levels from 401-700 mmHg)
0.1/0.1 mg/dL
1.7 to 22 0.01/0.01 mmol/L
Standard Reference Cassette (SRC) Limit Values
LOW NORMAL HIGH Units
40.0 ± 4.0 110.0 ± 4.0 300.0 ± 4.0 mg/dL
2.2 ±0.22 6.1 ±0.22 16.65 ±0.22 mmol/L
Interferences
The OPTI CCA Glucose sensor does exhibit interference from PO
2
levels that exceed 700 mmHg.
The Glucose sensor corrects for PO
2
values up to 700 mmHg. Glucose values are suppressed when PO
2
values are > 700 mmHg. This testing was done on the OPTI CCA platform, with a standard OPTI style
Glucose sensor. No changes were made to the sensor or the measurement principle, so the interference of
the OPTI CCA-TS2 is equivalent to the OPTI CCA.
Heparin salts are the only acceptable anticoagulants. Other anticoagulants such as citrate, EDTA, oxalate,
and uoride cause signicant interferences to the Glucose sensor.
Only clear, uncolored quality control materials, such as OPTI CHECK PLUS brand aqueous controls
should be used with the OPTI CCA-TS2 system. Colored materials, including prociency testing
materials, may interfere with the Glucose measurement, or fail to be properly aspirated.
To Next Page
Loading...
Need help?
General