6.3-1
Section 6
ApplicAtions
Pinnacle Operators Manual
Pickering Laboratories Inc.
residues of carbamates and their by-products may remain in the produce. The use of carbamate insecticides
has created a requirement for a simple, reliable, and sensitive method of residue analysis for these compounds
found in vegetable matter, drinking water, and industrial waste-water. The USEPA Methods 531.2 and 531.1,
and the AOAC International protocol 29.A05, describe a direct-inject method which employs gradient liquid
chromatography with fluorescence detection, accomplished by post-column hydrolysis and derivatization of the
eluted carbamates.
The general structure of the carbamate insecticides is an N-methyl substituted urethane with the variation in the
ester moiety. The structural formulas are shown in Figure 6.3-A.
OH
O
O
S
N
S
CH
3
CH
3
CH
3
CH
3
O
HN
OO
HN
CH
3
CH
3
CH
3
NH
H
3
C
O
O
O
O
H
3
C
S
N
CH
3
CH
3
NH
H
3
C
O
O
H
3
C
S
N
CH
3
CH
3
NH
H
3
C
O
O
O
H
3
C
S
N
CH
3
CH
3
NH
H
3
C
O
O
OH
CH
3
OO
HN
CH
3
H
3
C
Br
CH
3
OO
HN
CH
3
H
3
C
S
N
CH
3
CH
3
NH
H
3
C
O
O
CH
3
S
O
O
O
CH
3
CH
3
O
H
3
C
NH
O
O
CH
3
CH
3
CH
3
O
HN
Figure 6.3-A
Aldicarb Sulfoxide
Aldicarb Sulfone
Carbaryl
Methomyl
Aldicarb
3-Hydroxy Carbofuran
Propoxur
Oxamyl
Carbofuran
1-Naphthol
Methiocarb
BDMC
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