5.4
Section 5
Maintenance
Pinnacle Operators Manual
Pickering Laboratories Inc.
MANUAL SHUTDOWN
You may shutdown the Pinnacle PCX manually by pressing/selecting the Disable function in the Control menu
of the PCX control software.
If you choose this function, allow the HPLC to pump for at least 30 minutes to allow for the reactor to cool and
to flush reagent from the reactor.
OR
AUTOMATIC SHUTDOWN
Create a Shutdown Method for Pinnacle PCX according to section 4 of this manual. Set it up as the last
method in the Pinnacle PCX sequence. Make sure pump flow rate is set to 0 mL/min and reactor temperature
is set close to room temperature. You can leave the column at the operating temperature or set it at room
temperature.
Create corresponding slowdown Method for HPLC. Set it up as the last method in the HPLC sequence. Make
sure HPLC flushes column and reactor with column storage eluant for at least 30 min.
RECOMMENDED ACCOMPANYING HPLC SLOWDOWN METHOD
Set the HPLC to 100% Storage Eluant (see application section for proper eluant for your column), and set the
HPLC pump at the normal analytical flow rate. Choose an eluant that elutes contaminants from the column; for
example, methanol for a reversed-phase column and regenerant for an ion-exchange column.
Time (min) % Storage Eluant Flow (mL/min)
0 100 Analytical flow rate*
30 100 Analytical flow rate*
30.1 100 0.0
*Follow instructions that come with the column.
LONG-TERM SHUTDOWN
The above methods are used if the Pinnacle PCX will be used again within 3 days of the last run. If you plan to
not use the Pinnacle PCX for more than 3 days, we recommend that you use the Long-term Shutdown.
In this procedure, the reactor is flushed free from reagent, thus ensuring that it will be free from blockage
upon your return.
There are two ways to perform this shutdown; automatic, or manual.
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