PCO2 - 4 Art: 714182-00R Rev. Date: 02-Aug-11
Method Comparison (mmHg)
PCO
2
IL BGE
PCO
2
Radiometer ABL500
n 62 29
Sxx 0.69 0.74
Syy 1.24 0.53
Slope 1.003 1.016
Int’t -0.8 1.1
Sy.x 1.65 0.32
Xmin 30.4 28
Xmax 99.0 91
r 0.989 0.999
Factors Affecting Results*
Exposing the sample to air allows CO
2
to escape which causes PCO
2
to decrease and pH to increase
and HCO
3
and TCO
2
to be under-estimated. The use of partial-draw tubes (evacuated tubes that are
adjusted to draw less than the tube volume, e.g. a 5 mL tube with enough vacuum to draw only 3 mL)
is not recommended for use with the i-STAT System because of the potential for decreased measured
PCO
2
results and calculated HCO
3
and TCO
2
values. Under-filling blood collection tubes may also cause
decreased PCO
2
results. Care must also be taken to eliminate “bubbling” of the sample with a pipette when
filling a cartridge to avoid the loss of CO
2
in the blood.
Allowing blood to stand (without exposure to air) before testing allows PCO
2
to increase and pH to decrease,
which will cause HCO
3
and TCO
2
to be over-estimated, due to metabolic processes.
For patients administered propofol (Diprivan®) or thiopental sodium (syn. thiomebumal sodium,
penthiobarbital sodium, thiopentone sodium, thionembutal, Pentothal Sodium®, Nesdonal Sodium®,
Intraval Sodium®, Trapanal®, and Thiothal Sodium
7
), i-STAT recommends the use of G3+, CG4+, CG8+,
EG6+ and EG7+ cartridges, which are free from clinically significant interference at all relevant therapeutic
doses. i-STAT does not recommend the use of EC8+ cartridges for patients receiving propofol (Diprivan®)
or thiopental sodium.
* It is possible that other interfering substances may be encountered. These results are representative and your results may differ somewhat due to
test-to-test variation. The degree of interference at concentrations other than those listed might not be predictable.
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