PROCEDURE MANUAL FOR THE i-STAT SYSTEM
16
REV. DATE: 16-Oct-12 ART: 714446-00L
Interferences
An interferent is a substance which, if present at significant levels in the blood specimen being analyzed, will produce an
error in the result of the analyte being measured.
ANALYTE INTERFERENT INTERFERENT CONCENTRATION EFFECT ON ANALYTE RESULT
Sodium Bromide 37.5 mmol/L Increase () Na
Chloride Acetylcysteine
Bromide
Bromide (therapeutic)
Salicylate
Thiocyanate
10.2 mmol/L
37.5 mmol/L
2.5 mmol/L
4.34 mmol/L
6.9 mmol/L
Decrease () Cl
Increase () Cl
Increase () Cl
Increase () Cl
Increase () Cl
Ionized Calcium Acetominophen
Magnesium
Acetylcysteine
Bromide
Lactate
Salicylate (therapeutic)
Salicylate
1.32 mmol/L
1.0 mmol/L
10.2 mmol/L
37.5 mmol/L
6.6 mmol/L
0.5 mmol/L
4.34 mmol/L
Decrease () iCa
Increase () iCa by 0.04 mmol/L
Decrease () iCa
Increase () iCa
Decrease () iCa by 0.07 mmol/L
Decrease () iCa by approx. 0.03 mmol/L
Decrease () iCa
Glucose
(Cartridge)
Acetominophen
Acetylcysteine
Bromide
Bromide (therapeutic)
pH
Oxygen
Hydroxyurea
Thiocyanate
1.32 mmol/L
10.2 mmol/L
37.5 mmol/L
2.5 mmol/L
pH: per 0.1 pH units below 7.4 @ 37°C
pH: per 0.1 pH units above 7.4 @ 37°C
PO
2
less than 20 mmHg @ 37°C
0.92 mmol/L
6.9 mmol/L
Increase () glucose
Decrease () glucose
Decrease () glucose
Decrease () glucose result by approx.
5 mg/d/L
Decrease () glucose by 0.9 mg/dL (0.05
mmol/L)
Increase () glucose by 0.8 mg/dL (0.04
mmol/L)
May decrease () glucose
Increase () glucose
Decrease () glucose by approx. 7 mg/dL
Lactate
Bromide
Hydroxyurea
Glycolic Acid
37.5 mmol/L
0.92 mmol/L
10.0 mmol/L
Decrease () lactate
Increase () lactate
Increase () lactate
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