PROCEDURE MANUAL FOR THE i-STAT SYSTEM
17
REV. DATE: 16-Oct-12 ART: 714446-00L
ANALYTE INTERFERENT INTERFERENT CONCENTRATION EFFECT ON ANALYTE RESULT
Creatinine
<2 mg/dL
>2 mg/dL
Acetaminophen
Ascorbate
Bromide
PCO
2
PCO
2
Hydroxyurea
Acetylcysteine
Creatine
1.32 mmol/L
0.34 mmol/L
37.5 mmol/L
Above 40 mmHg
Below 40 mmHg
Above 40 mmHg
Below 40 mmHg
0.92 mmol/L
10.2 mmol/L
0.382 mmol/L
Increase () creatinine
Increase () creatinine by 0.3 mg/dL
Increase () creatinine
Increase () creatinine by 6.9% per 10
mmHg PCO
2
Decrease () creatinine by 6.9% per 10
mmHg PCO
2
Decrease () creatinine by 3.7% per 10
mmHg PCO
2
Increase () creatinine by 3.7% per 10
mmHg PCO
2
Increase () Creatinine. Use another
method
Increase () creatinine
Increase () creatinine by 0.2 mg/dL
Hematocrit White Blood Count
(WBC)
Total Protein
Lipids
Greater than 50,000 WBC/L
For measured Hct<40%
For each g/dL below 6.5
For each g/dL above 8.0
For measured Hct40%
For each g/dL below 6.5
For each g/dL above 8.0
Abnormally high
May Increase () hematocrit
Decrease () Hct by 1% PCV
Increase () Hct by 1% PCV
Decrease () Hct by 0.75% PCV
Increase () Hct by 0.75% PCV
Increase () Hct
Celite ACT Aprotinin Falsely extends Celite ACT times
PCO
2
Propofol (Diprovan
®
)
Thiopental Sodium
For patients administered propofol or
thiopental sodium, i-STAT recommends the
use of G3+, CG4+, CG8+, EG6+, and
EG7+ cartridges, which are free from
clinically significant interference at all
relevant therapeutic doses. i-STAT does
not recommend the use of EC8+ cartridges
for patients receiving propofol or thiopental
sodium.
PT/INR Cubicin
®
(daptomycin
for injection)
Chlorhexidine
Gluconate
Falsely extends prothrombin time (PT)
and INR
May falsely extend prothrombin time (PT)
and INR
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