REPLIGEN CTech FlowVPX System

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DOC0211

eRev. 1.08/15/2023

User Guide

CTech™ FlowVPX® System

2. Replace the gasket/seal pad between the Detector and Flow Cell every time a Flow Cell is loaded.

3. Replace the gasket/seal pad between the Flow Cell and Head every time a Flow Cell is loaded.

Perform a Transmission Check (Cary 60)

Perform a transmission check after each time a Flow Cell is loaded.

Clean the Flow Cell

Clean the Flow Cell by running 0.5 M NaOH for 30 minutes after a process run.

Check Connections

Ensure all of the connections to the FlowVPX Head are secure and fastened appropriately.

Protect Optical Surfaces

Protect the optical surfaces when the system is not in use. Flow Cells can be returned to their shipment cartons, the Delivery Fiber

should be capped and bagged, and the Detector can be stored in the Detector Validation Adapter with the Transmission Tool

attached.

Main Page

Table of Contents3
Table 1. Explanation of User Attention Phrases6
Table 2. Safety Precautions for the Flowvpx System6
Table 3. Regulatory Information7
Table 4. Mains Supply Information8
Figure 1. Ctech Flowvpx Instrument (Fully Assembled) Components11
Flowvpx Status Indicator Light12
Power and Integration Connector12
USB Communications Connector12
Figure 2. Flowvpx Head Components12
Flow Smart Input13
Storage13
Figure 3. Flowvpx Detector Components13
Figure 4. Flowvpx Flow Cell Components14
Figure 5. Flowvpx Standard Mount Components15
Figure 6. Flowvpx System Suitability Adapter (XSA) Components15
Transmission Tool16
Figure 7. Detector Validation Adapter (DVA) Components16
Figure 8. Transmission Tool and Sample Vessel Components16
The Flowvpx Power Cable (EC0205)17
The Flowvpx Power and I/O Splitter Cable (EC0208)17
The Flowvpx I/O External Cable (EC0214)17
The Flowvpx Extender Power Cable (EC0206)17
The Flowvpx USB Cable (EC0207)17
Figure 9. Flowvpx-Specific Cabling17
The Flowvpx Delivery Fiber18
Figure 10. Connecting Items and Tools18
Beams Source19
Figure 11. Cary 60 Spectrophotometer and Accessories19
Figure 12. Beams Source, Controller, and Accessories19
Beams Controller20
Flowvpx Detector Cable (EC0328)20
Beams Source 3 M Extender Cable (EC0337)20
Beams Detector 3 M Extender Cable (EC0338)20
Figure 13. Computer and Accessories20
Figure 14. Flowvpx Head (Logo Side Down)21
Figure 15. Standard Mount Clamp on Flowvpx Head21
Figure 16. 5 MM Ball End Driver21
Figure 17. Clamp Handle Installation22
Figure 18. Rotate Clamp Handle22
Figure 19. Tighten Mounting Post Clamp Handle22
Figure 20. Install Flowvpx Head on Mounting Post23
Figure 21. Lower Flowvpx Head on Mounting Post23
Figure 22. Tighten Standard Mount Clamp Handle (Left) and Repositioning the Clamp Handle (Right)23
Figure 23. Accessory Port in Back of Cary 60 Spectrophotometer24
Figure 24. Detector Cable in Sample Compartment24
Figure 25. Cary 60 Power Cable and USB Cable, Back Panel25
Figure 26. Fiber Optic Coupler Threaded Splice Bushing25
Figure 27. Connect Power and I/O Splitter Cable (EC0208) to Flowvpx Head25
Table 5. Flowvpx I/O Cable (EC0214) Pinout26
Figure 28. Flowvpx I/O Cable Connections26
Figure 29. I/O External Cable (EC0214) to Flowvpx Head26
Figure 30. USB Cable (EC0207) to Flowvpx Head27
Figure 31. Flowvpx USB Cable (EC0207) to Computer27
Figure 32. System Setup: Beams Controller Connections28
Figure 33. System Setup: Flowvpx Connections28
Figure 34. Beams Power Brick and Cable29
Figure 35. USB Computer Connections29
Figure 36. Viper Login Page30
Figure 37. My Applications: Quick Kinetics App30
Loading the Flow Cell Using the Cary 60 Light Source31
Figure 38. Method Input Menu: Select Flow Cell31
Figure 39. Load Button in Instrument Control Menu31
Figure 40. Flow Cell Loading Instructions32
Figure 41. Flow Cell Loading Window: Enter Serial Number33
Figure 42. Correct FX Connector Nut Orientation33
Loading the Flow Cell Using the Beams Light Source34
Figure 43. Flow Cell Loading Instructions (Beams)34
Figure 44. Correct Beams FX Connector Nut Orientation35
Unloading the Flow Cell Using the Cary 60 Light Source36
Figure 45. Unload Button in the Instrument Control Menu36
Figure 46. Unload Flow Cell Confirmation Prompt36
Unloading the Flow Cell Using the Beams Light Source37
Figure 47. Flow Cell Unloading Using the Cary 60 Light Source37
Figure 48. Flow Cell Unloading Using the Beams Light Source38
Figure 49. Transmission Check Button in Instrument Control Menu39
Figure 50. Transmission Check Instructions (Cary 60)40
Figure 51. Quick Check Button in Instrument Control Menu41
Figure 52. Quick Check Loading Window41
Figure 53. Quick Check Results42
Figure 54. My Applications: Validate VPT App43
Figure 55. System Suitability Button in Instrument Control Menu43
Figure 56. Start System Suitability Test Window44
Figure 57. System Suitability Test Instructions (Cary 60)44
Figure 58. Reference Standard Information Fields45
Running a Different Sample (Using a Cary 60 Light Source)46
Unloading the XSA Unit (Using a Cary 60 Light Source)46
Running a Different Sample (Using a Beams Light Source)48
Unloading the XSA Unit (Using a Beams Light Source)48
Table 6. Troubleshooting Issues and Responses49

REPLIGEN CTech FlowVPX System - Page 51

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