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eRev. 1.08/15/2023
15. Glossary
This glossary contains content developed by Repligen subject-matter experts or retrieved (whole or in part) from the American
Society for Quality glossary, the International Accreditation Forum website, and Spectroscopy magazine’s “The Molecular
Spectroscopy Terminology Guide” online.
Accuracy: The closeness of agreement between an observed value and an accepted reference or measured value.
Administrator: An individual with unlimited software application permissions who facilitates the installation and configuration of the
overall security plan.
Beams System: A monochromatic LED light source and data acquisition module for integration with the FlowVPX System, for single
wavelength applications.
Best Practice: A superior method or innovative practice that contributes to the improved performance of an organization, usually
recognized as best by other peer organizations.
Cary Spectrophotometer: A UV-Vis spectrophotometer manufactured by Agilent Technologies, which acts as both a light source and
analyzer for measuring absorbance signals.
Certification: The result of a person meeting the established criteria set by a certificate-granting organization.
Compliance: The state of an organization that meets prescribed specifications, contract terms, regulations or standards.
Data: The collection of numbers representing the direct results from actual measurements, and upon which calculations are to be
performed to determine the quantities of interest. Common data file formats for analytical spectroscopy include AB SCIEX Data
Explorer (.pkm), ASCII Table (.csv), Bruker (.XML), Excel (.xls), Finnegan (.asc), JCAMP-DX (.dx), MatLab (.mat), mzData (.XML),
PerkinElmer (.sp), Plain Text (.txt), Spectra-Calc, Archival, fixed point (.spc), Thermo Galactic (.spc), Thermo Scientific Nicolet (.SPA),
and XLM markup text (.XML).
Detector: A device used to detect light being transmitted through the sample.
Detector Cable: This component sends absorbance information from the VPT instrument to the Cary 60 spectrophotometer to be
analyzed and displayed for the user.
Detector Window: The transparent, protective cover of the VPT instrument’s Detector.
FC Connector Nut: Used to mate an optical component to another optical component. In the case of the FlowVPX, to mate the FC
Connector of the Delivery Fiber to the Flow Fibrette.
Fiber Optic Coupler: Directs light from the Cary 60 spectrophotometer into the Delivery Fiber for transmission to the VPT
Instrument.
Fibrette: The component of the FlowVPX System that delivers light from the Delivery Fiber to the sample for measurement. It allows
the measurement pathlength to be changed based upon its vertical motion within the sample.
Flow Cell: The in-line interface between the FlowVPX and the process flow to be measured. It creates a seal around the FlowVPX
Fibrette so the flow path remains enclosed.
Flow Cell Window: This is the bottom surface of the Flow Cell that allows light to pass through to the Detector Module.
Flow Fibrette: The component of the FlowVPX System that delivers light to the sample. Its position in the solution determines the
measurement pathlength as the Flow Head moves it up and down in the Flow Cell. There is a different Flow Fibrette based on the
size of the Flow Cell.
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